Search
for
Sort by
Research
30 / 1000+ resultsresearch A Facile and Biocompatible Hydrogel Based on Oxidized Brachybotrys paridiformis Polysaccharide for Enhanced Wound Healing
This study reported that a novel hydrogel wound dressing, created using a Brachybotrys paridiformis polysaccharide derivative and chitosan, significantly accelerated wound healing and tissue regeneration in vivo, showing nearly complete healing by day 15 compared to controls.
research ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata
In this study, researchers developed a biocompatible, ROS-responsive hydrogel to deliver miR-665 locally, effectively reducing inflammatory signaling and promoting hair follicle regeneration in an alopecia areata mouse model, offering a promising approach for targeted treatment.
research ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata
This study found that a newly developed biocompatible hydrogel, responsive to reactive oxygen species, enabled targeted delivery of miR-665, significantly promoting hair regeneration and reducing T-cell infiltration in a mouse model of alopecia areata, suggesting a promising strategy for treating this condition.
research Facile strategy for gelatin-based hydrogel with multifunctionalities to remodel wound microenvironment and accelerate healing of acute and diabetic wounds
This study demonstrates that an injectable gelatin-based hydrogel incorporating zirconium and quercetin promotes diabetic wound healing in vivo by enhancing angiogenesis, collagen deposition, and hair follicle regeneration while providing antibacterial and oxidative stress protection without detectable cytotoxicity.
research Recent Advances in Biodegradable and Biocompatible Synthetic Polymers Used in Skin Wound Healing
This review highlights that synthetic biodegradable polymers like PVA, PCL, PLA, PLGA, PU, and PEO/PEG can address the limitations of natural polymers in wound healing, offering improved mechanical properties and slower degradation, thereby enhancing their application as wound dressings.
research ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata
This study reports that a new ROS-responsive hydrogel platform delivering miR-665 effectively reduced inflammation and promoted hair follicle regeneration in AA, suggesting a promising treatment approach.
research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With an Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability
This study found that adapalene-loaded nanospheres in a hyaluronic acid gel enhanced skin penetration and were nonirritant, making them potentially suitable for treating acne on oily skin.
research Biodegradable Polysaccharide Gels for Skin Scaffolds
This paper describes the development of unique hydrogel skin scaffolds from plant-derived polysaccharide mixtures that may offer improved biocompatibility and mechanical properties for use in artificial skin.
research Engineering Robust Ag‐Decorated Polydopamine Nano‐Photothermal Platforms to Combat Bacterial Infection and Prompt Wound Healing
This study demonstrated that incorporating PDA@Ag nanoparticles into a cationic guar gum hydrogel significantly enhanced photothermal conversion efficiency, achieving superior antibacterial efficacy both in vitro and in vivo, advancing the potential of PDA as a photothermal antibacterial agent.
research [Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation
Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
research Herbal Nanoemulgel-: A Comprehensive Review On Formulation, Mechanism, Characterization And Method Of Preparation
This review concludes that herbal nanoemulgel-based hair dyes, incorporating natural ingredients, enhance dye penetration and retention while providing additional hair and scalp health benefits compared to conventional dyes, though further studies are needed to confirm long-term safety and efficacy.
research Herbal Nanoemulgel-: A Comprehensive Review On Formulation, Mechanism, Characterization And Method Of Preparation
This review highlights that herbal nanoemulgel-based hair dyes, enriched with natural ingredients, improve dye penetration and retention and offer additional hair and scalp benefits compared to conventional dyes, although further research is necessary to verify their safety and efficacy for long-term use.
research Composite HydrogelBased on Green Chlorella Polysaccharide–SeleniumNanoparticles for Simultaneous WoundTreatment and pH Monitoring
This study developed a novel hydrogel combining Chlorella extracellular polysaccharide–selenium nanoparticles (EPS-SeNPs) with biocompatible components, which demonstrated strong antibacterial and anti-inflammatory effects, significantly accelerating wound healing in an infected rat model, and enabling pH-based monitoring of healing.
research Fabrication and biological evaluation in vivo of an injectable keratin hydrogel as filler materials
This study found that keratin hydrogels extracted from human hair showed potential as biodegradable and biocompatible filler materials, promoting angiogenesis and cell proliferation in rat models.
research Effect of injectable calcium alginate-amelogenin hydrogel on macrophage polarization and promotion of jaw bone osteogenesis
This study found that an injectable calcium alginate-amelogenin hydrogel is biocompatible, degradable, anti-inflammatory, and promotes osteogenesis, which may enhance the bone healing process in jaw and facial bone defect areas by mediating the bone immune microenvironment.
research Preparation and characterization of keratin-based biocomposite hydrogels prepared by electron beam irradiation
Keratin-based hydrogels from human hair and wool are promising for wound dressings and are more eco-friendly.
research Keratin biomaterials for wound healing and tissue regeneration: A promising approach in biomedical applications
This study highlights keratin biomaterials as a promising biocompatible option for wound healing and tissue regeneration but notes that further clinical studies are necessary to confirm their effectiveness.
research Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications
This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.
research Engineering a bacterial polysaccharide-based metal–organic framework-enhanced bioactive 3D hydrogel for accelerated full-thickness wound healing
This study found that a multifunctional hydrogel dressing enriched with Cu-MOF and tannic acid significantly improved full-thickness wound healing in rats, reducing the wound area to only 1.6% and promoting re-epithelialization, neovascularization, and hair follicle formation.
research Hydrogel-Forming Microneedles in the Management of Dermal Disorders Through a Non-Invasive Process: A Review
This review discusses hydrogel-forming microneedles for non-invasive drug delivery in dermatology and reports no new clinical results, emphasizing their promise in improving treatment adherence and patient comfort.
research Reduced graphene oxide/mesoporous cerium oxide nanoparticles-loaded PVA hydrogel with anti-inflammatory, antioxidant effect and acute wound healing promotion under electrical stimulation
This study reported that a newly designed multifunctional conductive hydrogel, PrM, combined with electrical stimulation significantly accelerated wound healing, achieving 95.9% healing in a mouse model on day 10, by enhancing regenerative processes and downregulating TNF-α signaling under electrical treatment.
research Flutamide-Loaded Zein Nanocapsule Hydrogel, a Promising Dermal Delivery System for Pilosebaceous Unit Disorders
The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
research Progress in Pluronic F127 Derivatives for Application in Wound Healing and Repair
This review discusses the potential of Pluronic F127-derived hydrogels for wound healing, examining their applications in various wound types and exploring underlying mechanisms and their interaction within the wound microenvironment.
research Microneedle patch encourages hair to regrow
In this study, a patch with microneedles regrew hair in shaved mice within six days, suggesting potential for treating hair loss in humans.
research Facile General Injectable Gelatin/Metal/Tea Polyphenol Double Nanonetworks Remodel Wound Microenvironment and Accelerate Healing
This study found that injectable gelatin/metal/tea polyphenol double nanonetworks significantly accelerated wound healing in diabetic wounds by enhancing cell migration and providing anti-inflammatory and antioxidant properties, without detectable cytotoxicity in tests.
research Magnetically driven formation of 3D freestanding soft bioscaffolds
This study introduces a magnet-assisted fabrication strategy for creating complex 3D soft bioscaffolds, demonstrating its effectiveness by producing structures with overhangs and supporting biohybrid actuators, promising advancements in biomedical applications.
research Adaptive Gelatin Microspheres Enhanced Stem Cell Delivery and Integration With Diabetic Wounds to Activate Skin Tissue Regeneration
This study found that gelatin microspheres delivering adipose-derived stem cells significantly accelerated diabetic wound healing in rats, suggesting a promising approach for enhancing cell-based therapies.
research Regeneration of Peripheral Nerves Using Neuroinductive Biomaterial Scaffolds
This study found that keratin biomaterials derived from human hair promoted significant motor function recovery and neuromuscular regeneration in animal models of peripheral nerve injuries.
research Self-Assembled Berberine-Sinapic Acid Nanomedicine for Synergistic Chemotherapy
This study reported that a novel nanomedicine combining berberine and sinapic acid significantly inhibited the growth of mouse mammary carcinoma cells and demonstrated an anti-tumor effect in vivo, without significant systemic toxicity after 28 days, suggesting a promising, low-toxicity therapeutic strategy for breast cancer.