TLDR Biodegradable polysaccharide gels can improve skin healing and reduce scarring.
The document discussed the development of biodegradable and biocompatible hydrogel skin scaffolds made from plant-extracted polysaccharide mixtures. These hydrogels were designed to address the limitations of existing skin substitutes, such as the risk of latent viruses in skin-derived substitutes and scarring in artificial grafts. The polysaccharide hydrogels exhibited a range of mechanical and degradation properties, aiming to mimic the diverse functions of natural skin, including protection, cell compatibility, biodegradation, and the release of signals necessary for cell growth and wound healing.
72 citations
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December 1996 in “Journal of Investigative Dermatology” Human hair follicles can regenerate after removal, but with low success rate.
78 citations
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February 2024 in “ACS Omega” The scaffold is a promising material for wound healing and tissue engineering.
25 citations
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November 2022 in “Frontiers in Bioengineering and Biotechnology” Composite biodegradable biomaterials can improve diabetic wound healing but need more development for clinical use.
April 2024 in “Journal of composites science” Hydrogel composites have great potential in regenerative medicine, tissue engineering, and drug delivery.
Plant-based compounds can improve wound dressings and skin medication delivery.
76 citations
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February 2024 in “International Journal of Molecular Sciences” Hydrogels show promise for improving skin wound healing.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.