research Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
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research Pharmacokinetic Interaction Between Finasteride and Terazosin, but Not Finasteride and Doxazosin
Finasteride interacts with terazosin, but not doxazosin; caution needed.
research Eruptive Vellus Hair Cysts: An Underdiagnosed Entity
Eruptive vellus hair cysts are often missed in diagnoses.
research Anti-Androgens
Effective treatments for excessive body hair in women include drugs that block androgens, sometimes combined with oral contraceptives.
research Risk of Age-Related Macular Degeneration in Men Receiving 5α-Reductase Inhibitors: A Population-Based Cohort Study
Men taking dutasteride may have a higher risk of age-related macular degeneration.
research Association of 5α-Reductase Inhibitors With Depression and Suicide: A Mini Systematic Review and Meta-Analysis
Drugs for prostate enlargement and hair loss were not linked to increased risk of depression or suicide.
research The Clinical Development of a 5α-Reductase Inhibitor, Finasteride
Finasteride effectively treats BPH, but needs more trials to understand potential.
research The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients
Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.
research Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction
Finasteride helps reduce heart issues and improves heart function.
research Dutasteride
Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
research Validated HPTLC Method for the Simultaneous Determination of Alfuzosin, Terazosin, Prazosin, Doxazosin, and Finasteride in Pharmaceutical Formulations
Method can accurately measure five BPH drugs at once.
research The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride reduces response to stress and rewards, affecting behavior and mental health.
research Trichofolliculoma: Case Report with Immunohistochemical Study of Cytokeratins
Trichofolliculoma has specific cytokeratin patterns that help in its diagnosis.
research Discontinuation of Alpha-Blockade After Initial Treatment With Finasteride and Doxazosin for Bladder Outlet Obstruction
Stopping alpha-blocker medication after 6-9 months is safe and effective for most patients with bladder outlet obstruction.
research Anti-Androgenic Therapy with Finasteride Improves Cardiac Function, Attenuates Remodeling, and Reverts Pathologic Gene Expression After Myocardial Infarction in Mice
Finasteride improves heart function and repairs damage after heart attack in mice.
research Finasteride Treatment and Neuroactive Steroid Formation
Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
research Adverse Cutaneous Effects of Psychotropic Medications
Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.
research Successful Treatment of Eccrine Angiomatous Hamartoma Using Combined Sequential Pulsed Dye Laser and Nd:YAG Laser
Two cases of a rare skin condition were successfully treated with laser therapy, offering a non-surgical treatment option.
research Spectrophotometric Method for the Estimation of Finasteride in Tablets
A new method accurately measures finasteride in tablets using color change and light absorption.
research A Retrospective Study of Clinical Outcomes of Alpha-Blocker or Finasteride Monotherapy Followed by Combination Therapy: Determination of the Period of Combination Therapy of Alpha-Blocker and Finasteride
Combination therapy for 9+ months maintains symptom improvements after stopping alpha-blockers or finasteride.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Bullous Pilomatrixoma: Without a Shadow of Doubt – Role of ROSE and Cytology
Fine needle aspiration with rapid on-site evaluation is useful for diagnosing pilomatrixoma.
research Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Ovarian Leydig Cell Hyperplasia as a Rare Cause of Hair Loss in a Postmenopausal Female Patient: A Case Report and Diagnostic Approach Toward Postmenopausal Hyperandrogenism
An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.
research Reply to Finasteride and Dutasteride May Reduce Melanoma Risk
Finasteride and dutasteride may lower melanoma risk, with teenage acne possibly indicating higher risk.
research Lymphomatoid Papulosis Improving on Hormone-Replacement Therapy
Hormone-replacement therapy improved a woman's skin condition known as lymphomatoid papulosis.
research Tamsulosin Versus Finasteride: Effect on Bother and Urinary Flow
Tamsulosin works faster, but both drugs have similar effects after 6 months.
research Black Hairy Tongue: A Case Report
Improving oral hygiene and quitting smoking can resolve black hairy tongue.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research Atypical Manifestation of Giant Epidermal Cyst Over Sacrococcygeal Region in Elderly Male
An elderly man had a rare, large skin cyst on his lower back, which was removed by surgery.