Risk of Age-Related Macular Degeneration in Men Receiving 5α-Reductase Inhibitors: A Population-Based Cohort Study

    July 2024 in “ Age and Ageing ”
    Yu‐Chen Su, Chin‐Yao Shen, Shih‐Chieh Shao … Edward Chia‐Cheng Lai
    Studysummary In this retrospective, population-based cohort study, researchers found no significant difference in age-related macular degeneration incidence between BPH patients using 5α-reductase inhibitors and those on tamsulosin, but observed a slight increased risk with dutasteride compared to finasteride.
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    Research cited in this study 8

    1. Androgenetic Alopecia: Therapy Update Drugs · 2023
    2. Macular Abnormalities Associated With 5α-Reductase Inhibitor JAMA Ophthalmology · 2020
    3. Incidence of Type 2 Diabetes Mellitus in Men Receiving Steroid 5α-Reductase Inhibitors: Population-Based Cohort Study BMJ. British medical journal · 2019
    4. Association Between Male Pattern Baldness and Prostate Disease: A Meta-Analysis Urologic Oncology: Seminars and Original Investigations · 2017
    5. Appropriateness of Oral Drugs for Long-Term Treatment of Lower Urinary Tract Symptoms in Older Persons: Results of a Systematic Literature Review and International Consensus Validation Process (LUTS-FORTA 2014) Age and Ageing · 2015
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    8. Comparison of Clinical Trials with Finasteride and Dutasteride PubMed · 2004