A Retrospective Study of Clinical Outcomes of Alpha-Blocker or Finasteride Monotherapy Followed by Combination Therapy: Determination of the Period of Combination Therapy of Alpha-Blocker and Finasteride
April 2013
in “
International Journal of Clinical Practice
”
TLDR Combination therapy for 9+ months maintains symptom improvements after stopping alpha-blockers or finasteride.
This study investigated the outcomes of discontinuing alpha-blockers or finasteride in patients who initially received combination therapy for benign prostatic hyperplasia (BPH). The study found that discontinuation of alpha-blockers or finasteride after combination therapy for more than 6 months maintained improvements in symptoms. The appropriate period of combination therapy was found to be 9 months or longer. The study also showed the superior effect of improvement in symptom scores over alpha-blocker or finasteride monotherapy.
