TLDR Trichofolliculoma has specific cytokeratin patterns that help in its diagnosis.
The document presented a case report on trichofolliculoma, a rare benign hair follicle tumor, and included an immunohistochemical study focusing on cytokeratins. The study was conducted by a team from various departments in Japan, including dermatology, plastic and reconstructive surgery, and pathology. The findings highlighted the specific expression patterns of cytokeratins in trichofolliculoma, contributing to a better understanding of its histopathological characteristics. This research provided valuable insights into the diagnosis and differentiation of trichofolliculoma from other skin lesions.
17 citations,
June 2017 in “British Journal of Dermatology” The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
7 citations,
March 2017 in “Journal of dermatology” The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.
16 citations,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
19 citations,
September 2016 in “Journal of the European Academy of Dermatology and Venereology” Trichofolliculoma is a unique benign tumor mainly affecting middle-aged adults' faces, often misdiagnosed without histopathology.
8 citations,
January 2014 in “Annals of Dermatology” The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.
