106 citations
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January 2013 in “Clinical and Developmental Immunology” This review discusses the pathogenesis of alopecia areata, highlighting the role of immune privilege collapse in hair follicles but reports no clinical results.
48 citations
,
September 2020 in “Frontiers in Immunology” In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.
44 citations
,
February 2023 in “Cell” In this study, researchers found that human fingerprint ridges are formed through a modified hair follicle developmental process and spatial patterns influenced by specific signaling pathways.
33 citations
,
August 2008 in “American Journal Of Pathology” This study found that K6a expression in mouse sebaceous gland ducts correlates with Hedgehog signaling, suggesting a role in duct fate.
26 citations
,
January 2020 in “Dermatology Online Journal” This study found that livedoid and acro-ischemic skin manifestations were significantly associated with severe COVID-19, while chilblains-like eruptions appeared in less severe cases.
21 citations
,
March 2021 in “Frontiers in Neurology” This review explores how adaptive changes in cerebellar and vestibular subsystems may contribute to balance control, noting cellular mechanisms involved, but presents no new clinical findings.
20 citations
,
December 2020 in “Frontiers in Immunology” This study found that certain T cell-associated genes were upregulated in dogs with Vogt-Koyanagi-Harada syndrome and vitiligo, suggesting a shared immunopathogenesis with humans.
16 citations
,
January 2022 in “International journal of molecular sciences” This review summarizes the influences of lifestyle factors such as smoking, alcohol, and diet on the pathogenesis of alopecia areata but reports no new clinical results.
15 citations
,
August 2022 in “The Application of Clinical Genetics” This review describes the clinical presentation, diagnosis, and management of adrenomyeloneuropathy, including rehabilitative therapies and spasticity management, and reports no new clinical results.
10 citations
,
November 2024 in “Animals” This review examines the genetic challenges in improving wool and cashmere fibers, emphasizing the need for further research on wool keratins and keratin-associated proteins to enhance fiber characteristics.
8 citations
,
August 2019 in “ACR Open Rheumatology” This review explores the biomechanical factors and signaling systems, like Wnt, involved in the pathophysiology of psoriatic nail lesions and reports no new results.
5 citations
,
December 2016 in “Journal of skin and stem cell” This study found that patients with cutaneous lichen planus had a higher risk of metabolic syndrome, dyslipidemia, diabetes mellitus, and hypertension compared to controls.
3 citations
,
May 2023 in “Frontiers in Public Health” In this study, 76% of hospitalized COVID-19 patients experienced post-COVID-19 syndrome with symptoms like difficulty concentrating and fatigue lasting around 150 days, significantly impacting their quality of life through increased pain, discomfort, and anxiety.
3 citations
,
January 2023 in “International journal of molecular sciences” In this study, researchers found that miR-143-3p may play a novel role in cashmere growth by directly repressing the expression of Itga6 in secondary hair follicles of goats.
3 citations
,
March 2019 in “Case Reports” This report highlights a case of possible association between myotonic dystrophy type 1 and basal cell carcinoma, urging clinicians to consider this link despite negative genetic testing for known hereditary BCC syndromes.
2 citations
,
December 2019 in “The Open Dermatology Journal” This article describes the first reported case of isolated linear discoid lupus erythematosus on the scalp, suggesting it should be considered in the differential diagnosis of linear scarring alopecia.
1 citations
,
September 2025 in “Frontiers in Immunology” This study reviewed the expression of chemokines in patients with alopecia areata, finding elevated Th1 and Th2 chemokine levels, suggesting a complex immune profile that may require broad immunomodulatory strategies to address the disease's underlying immune dysregulation.
1 citations
,
January 2023 in “Journal of Clinical Medicine” This paper presents the first reported case of Acute Localized Exanthematous Pustulosis linked to topical minoxidil use, suggesting a contact-induced hypersensitivity reaction as a potential mechanism.
1 citations
,
April 2020 in “medRxiv (Cold Spring Harbor Laboratory)” This study identified gene sets associated with Tourette Syndrome, implicating Ligand-gated Ion Channel Signaling, Lymphocytic, and Cell Adhesion and Trans-synaptic Signaling processes in the disorder's neurobiology.
In this study, Fgf20 was found to trigger movement and morphogenesis in dermal fibroblasts, facilitating dermal condensate formation essential for hair follicle development.
January 2026 in “International Journal of Molecular Sciences” In this study, researchers identified S100a4 as a critical regulator of secondary hair follicle stem cells in cashmere goats, linking its expression to follicle regeneration and differentiation pathways, which may have implications for enhancing cashmere fiber production.
September 2025 in “Diseases” This study found that patients with patchy alopecia areata had significantly higher serum levels of pro-inflammatory cytokines IL-6, TNF-α, IL-17A, and IL-21 compared to healthy controls, with these levels correlating positively with disease severity, age, and disease duration.
July 2025 in “Journal of the Dermatology Nurses’ Association” This article reports on the 2025 Annual Dermatology Nurses’ Association Convention, emphasizing its role in education, networking, and advocacy advice, and provides insights into managing stress-related skin issues and hair loss, as well as dermatology treatment advances.
This study concluded that oral tofacitinib significantly improved hair growth in patients with alopecia areata, alopecia totalis, and alopecia universalis over a 24-week period, but longer studies are needed to assess long-term safety.
February 2025 in “International Journal of Molecular Sciences” This study found that melatonin may enhance hair follicle stem cell viability by downregulating the nuclear receptor RORA, which otherwise inhibits cell proliferation and promotes apoptosis.
January 2025 in “Frontiers in Genetics” In this study, researchers reported significant hair growth in an 8-year-old with hypotrichosis simplex of the scalp after treatment with a combination of oral botanical extracts and minoxidil, marking the first documented use of botanical extracts as a potential therapeutic approach for this condition.
This study observed that TBX3 mRNA expression levels were region-specific and correlated with pigmentation patterns in dun Mongolian horses, providing insights into the genetic mechanisms behind their distinctive Bider markings.
November 2024 in “Comparative Biochemistry and Physiology Part D Genomics and Proteomics” In this study, epithelial cell-derived exosomes promoted fibroblast migration and inhibited their proliferation, suggesting a role in dermal condensate formation and hair follicle morphogenesis in cashmere goats.
November 2024 in “The Medical Journal of Australia” This personal account described enduring long COVID symptoms for four years following a COVID-19 infection, significantly impacting the author's career, lifestyle, and mental health, ultimately leading to early retirement and a move to a low-maintenance living community.
January 2024 in “Pan African Medical Journal” This study aimed to document and compare the prevalence and characteristics of hair loss in patients with systemic lupus erythematosus, noting the differences in trichoscopic and histopathologic evaluations between those with and without alopecia. Results are not reported.