Exosomes as Crucial Mediators of Epithelial-Fibroblast Communication During Hair Follicle Morphogenesis in Cashmere Goats

    Erhan Hai, Chenglin Wang, Zhihong Wu
    🚨 The study is relevant to hair biology and follicle development, but it focuses on cashmere goats, which limits its direct applicability to human hair loss treatments or conditions.
    Studysummary In this study, epithelial cell-derived exosomes promoted fibroblast migration and inhibited their proliferation, suggesting a role in dermal condensate formation and hair follicle morphogenesis in cashmere goats.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 15

    1. Exosomes for Hair Growth and Regeneration Journal of Bioscience and Bioengineering · 2023
    2. Dermal Papilla Cell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1 International Journal of Molecular Sciences · 2023
    3. Screening of MicroRNA and mRNA Related to Secondary Hair Follicle Morphogenesis and Development and Functional Analysis in Cashmere Goats Functional & Integrative Genomics · 2022
    4. Exosomal miRNA-181a-5p from Hair Follicle Dermal Papilla Cells Promotes Hair Follicle Growth and Development via the Wnt/β-Catenin Signaling Pathway International journal of biological macromolecules · 2022
    5. Exosomes Derived From Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation Through The Wnt3a/Beta-Catenin Signaling Pathway Oxidative Medicine and Cellular Longevity · 2022
    6. Generation of VEGF Knock-In Cashmere Goat via the CRISPR/Cas9 System International Journal of Biological Sciences · 2021
    7. Using WGCNA to Identify Hub Genes of Skin Hair Follicle Development in Fetal Stage of Inner Mongolia Cashmere Goat PloS one · 2020
    8. Chi-MiR-130b-3p Regulates Inner Mongolia Cashmere Goat Skin Hair Follicles in Fetuses by Targeting Wnt Family Member 10A G3 Genes Genomes Genetics · 2020
    9. The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics International Journal of Molecular Sciences · 2019
    10. High-Throughput Sequencing of Hair Follicle Development-Related MicroRNAs in Cashmere Goat at Various Fetal Periods Saudi Journal of Biological Sciences · 2017
    11. Genome-Wide Target Enrichment-Aided Chip Design: A 66K SNP Chip for Cashmere Goat Scientific reports · 2017
    12. The Hair Follicle Enigma Experimental Dermatology · 2017
    13. MicroRNAs in Skin Tissue Engineering Advanced drug delivery reviews · 2015
    14. Control by a Hair’s Breadth: The Role of MicroRNAs in the Skin Cellular and Molecular Life Sciences · 2012
    15. The Secret Life of the Hair Follicle Trends in genetics · 1992

    Related research 6

    1. Single-Cell Sequencing Reveals the New Existence Form of Dermal Papilla Cells in the Hair Follicle Regeneration of Cashmere Goats Genomics · 2022
    2. Shedding Light on Cashmere Goat Hair Follicle Biology: From Morphology Analyses to Transcriptomic Landscape BMC genomics · 2020
    3. Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Hair Follicle Cycling in Cashmere Goats Research Square (Research Square) · 2019
    4. Hair Follicle Transcriptome Profiles During the Transition from Anagen to Catagen in Cashmere Goat (Capra Hircus) Genetics and molecular research · 2015
    5. Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat Skin During Hair Follicle Development and Cycling PloS one · 2013
    6. Hoxc13/β-Catenin Correlation with Hair Follicle Activity in Cashmere Goat Journal of integrative agriculture/Journal of Integrative Agriculture · 2012