Multiple Basal Cell Carcinomas in a Patient with Myotonic Dystrophy Type 1

    March 2019 in “ Case Reports ”
    Jessica Feng, Avery LaChance, David A. Sinclair, Maryam M. Asgari
    Image of study
    TLDR A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.
    In 2019, a case study was conducted on a man in his 60s with myotonic dystrophy type 1 (DM1) who had 28 primary basal cell carcinomas (BCC) and four squamous cell carcinomas. Genetic testing ruled out known hereditary BCC-associated syndromes. The study suggested a link between DM1 and BCC, possibly due to the mutated DMPK gene in DM1 patients interfering with protein production, DNA repair, and cell death. This was the ninth reported case of DM1 associated with multiple, early-onset BCCs. The study emphasized the need for sun protection and skin cancer surveillance in DM1 patients, and the involvement of dermatologists in their care.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 17 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 1 year ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

    Similar Research

    5 / 1000+ results