144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
September 2018 in “Journal of Investigative Dermatology” Non-white organ transplant patients have worse skin cancer outcomes due to later diagnosis and treatment.
70 citations,
August 1995 in “Fertility and Sterility” Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.
4 citations,
April 1986 in “Cancer Letters” GSH-T levels in hair follicles are similar in smokers and non-smokers and don't increase with certain treatments.
18 citations,
August 2011 in “Medical Hypotheses” Physical inactivity is a primary cause of many human illnesses.
172 citations,
December 2004 in “Journal of The American Academy of Dermatology” Demodicosis is common and often missed, needing more recognition and treatment in skin care.
Early detection and comprehensive treatment of PCOS are crucial due to its long-term health impacts and associated risks.
25 citations,
May 2018 in “Clinical & Translational Oncology” New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
June 2016 in “Annals of the rheumatic diseases” Methotrexate is effective for treating rheumatoid arthritis but requires regular monitoring.
136 citations,
February 2017 in “International Journal of Molecular Sciences” PRP treatment improves hair growth, and the device used can affect results, with some being more effective.
130 citations,
September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
98 citations,
May 2008 in “British Journal of Dermatology” There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
62 citations,
April 2004 in “Expert Opinion on Pharmacotherapy” Finasteride effectively treats male pattern baldness, improving hair growth and density.
52 citations,
June 1999 in “Endocrinology and Metabolism Clinics of North America” Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.
36 citations,
September 1999 in “Toxicologic pathology” Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.
26 citations,
November 1993 in “Progress in Neuro-psychopharmacology & Biological Psychiatry” Treatment during development affects hormone balance and sexual behavior in male rats.
24 citations,
March 2002 in “Expert opinion on investigational drugs” Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
18 citations,
May 2013 in “Journal of Dermatological Treatment” Non-ablative fractional laser treatments have a low risk of side effects in Asian patients.
9 citations,
September 2000 in “Obstetrics and gynecology clinics of North America” Hirsutism causes significant psychological distress in women.
75 citations,
November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
54 citations,
December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
29 citations,
July 2009 in “BJU international” Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
9 citations,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
44 citations,
January 2005 in “Dermatology” Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.
23 citations,
February 2014 in “Journal of Pediatric and Adolescent Gynecology” Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.
17 citations,
November 2002 in “Australasian Journal of Dermatology” Saw palmetto causes allergic reaction, minoxidil causes skin irritation; use cautiously for hair loss.
Low-level laser therapy combined with Neoptide improved hair regrowth better than either treatment alone in rats.
305 citations,
March 2018 in “International journal of molecular sciences” The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
50 citations,
April 2000 in “Fertility and Sterility” Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.
29 citations,
September 2004 in “Fertility and Sterility” Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.