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Human skin can make serotonin and melatonin, which help protect and maintain it.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Liposomes could improve how skin care products work but are costly and not very stable.

Spironolactone most effective for hirsutism, but has side effects.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Mice with human skin protein K8 had more skin problems and cancer.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Obese people have more skin problems like stretch marks and infections, which get worse with higher obesity levels.

Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Different lab conditions and light treatment methods change how human skin cells respond to light therapy.

Finasteride reduces hair growth and is safe for women with excessive hair.