September 1997 in “Dermatologic Surgery” This article reviews different grafting strategies for hair restoration surgery in extensive baldness and suggests uniform density grafting offers less detectable results, especially under adverse grooming conditions.
April 2019 in “Journal of emerging technologies and innovative research” This article discusses female pattern baldness and effective treatments like oral anti-androgens and topical minoxidil for managing its progression and reversing hair follicle shrinkage, but reports no new findings.
This study found that both finasteride and low level laser therapy were similarly effective in improving hair regrowth for frontal pattern hair loss in men and women over a 3-month period.
August 2002 in “Zeitschrift für Hautkrankheiten” This review discusses female pattern hair loss, suggesting it involves both androgen-dependent and independent factors, but it reports no new clinical results.
20 citations
,
September 2021 in “Nature communications” In this study, researchers identified a gene expression pre-pattern and implicated the Wnt inhibitor Dickkopf 4 in the formation of color patterns in domestic cat embryos.
October 2019 in “International journal of clinical & experimental dermatology” This study found that female pattern hair loss significantly reduces quality of life, particularly among younger patients, those with longer disease duration, and individuals with diagnosed mental health issues.
133 citations
,
February 2017 in “PLoS Genetics” In this study, researchers used genetic data from over 52,000 men to identify over 250 genetic loci associated with severe hair loss and developed a predictive algorithm for determining hair loss risk.
58 citations
,
July 1986 in “Journal of The American Academy of Dermatology” Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.
57 citations
,
November 2017 in “Nature Communications” This genome-wide association study identified 71 genetic loci linked to male pattern baldness, with 30 novel loci, explaining 38% of the risk and suggesting shared pathways with lifespan and cancer traits.
37 citations
,
October 2015 in “European Journal of Human Genetics” This study found that a genetic model using SNPs can predict early-onset male-pattern baldness with moderate accuracy, which may assist in decisions about interventions.
28 citations
,
September 2014 in “Journal of Clinical Oncology” This study observed that frontal plus moderate vertex baldness at age 45 was associated with a higher risk of aggressive prostate cancer in a large cohort.
16 citations
,
October 2012 in “The Journal of Dermatology” This study found that the BASP classification system for pattern hair loss showed better reproducibility and repeatability compared to the Norwood-Hamilton classification.
4 citations
,
December 2011 in “Journal of The American Academy of Dermatology” This study found that higher cumulative doses of topical minoxidil solution were strongly associated with improved hair density and thickness in male patients with androgenic alopecia over a 24-week period.
1 citations
,
March 2025 in “Frontiers in Physiology” This study identified key genes linked to immune cells and potential therapeutic compounds for alopecia areata by evaluating upregulated genes from patient datasets, highlighting T and NK cell involvement in hair follicle attack and suggesting drug candidates through molecular docking and dynamics simulations.
1 citations
,
January 2017 in “ARC journal of dermatology” This study introduced and evaluated Ahmad's NPRT system for documenting hair loss, finding it helpful in assessing the specific state of male pattern baldness in 500 patients.
47 citations
,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” This article reviews the generation of complex integument patterns through genetic, chemical, and environmental influences, with applications in tissue engineering, but reports no new experimental results.
46 citations
,
February 2016 in “Experimental Dermatology” This review discusses the genetic research developments in androgenetic alopecia, reporting no new clinical results, and highlights the potential for discovering novel therapeutic targets.
19 citations
,
September 2014 in “British Journal of Dermatology” This study found that topical minoxidil 5% foam was effective in promoting hair growth in both the frontal and vertex scalp for men with androgenetic alopecia.
3 citations
,
May 2021 in “Dermatologic Clinics” This article reviews potential therapeutic targets and comorbidities associated with male androgenetic alopecia, but reports no new clinical results; further study is needed for comprehensive management.
May 1993 in “Medical Clinics of North America” This article discusses male pattern alopecia and current hair replacement surgical techniques, without presenting new clinical findings.
21 citations
,
May 2016 in “The Cochrane library” This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
15 citations
,
July 2020 in “Dermatologic Therapy” This review discusses the pathophysiology, diagnosis, systemic associations, and treatments for female pattern hair loss and reports no new clinical findings.
215 citations
,
November 2006 in “Journal of The American Academy of Dermatology” This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.
212 citations
,
September 2008 in “Journal of The American Academy of Dermatology” This review discusses the various treatment options for male and female pattern hair loss and provides no new clinical results; the authors outline the most effective strategies based on existing evidence.
203 citations
,
December 2004 in “Journal of The American Academy of Dermatology” This article reviews the historical developments in understanding and treating male pattern hair loss, emphasizing the role of dihydrotestosterone and 5α-reductase inhibitors, but reports no new clinical findings.
158 citations
,
February 2000 in “Archives of dermatology” This study reports that some patients with androgenetic alopecia may also exhibit clinical and histological features of inflammation and fibrosis, similar to those found in lichen planopilaris.
149 citations
,
July 2017 in “PLoS Biology” This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.
134 citations
,
April 2020 in “Journal of Cosmetic Dermatology” Male pattern hair loss could hint at androgens affecting COVID-19 severity.
92 citations
,
June 2010 in “Journal of The American Academy of Dermatology” This study found that 0.5 mg of dutasteride significantly improved hair growth compared to placebo and was well tolerated over six months in men with male pattern hair loss.
87 citations
,
March 2011 in “Australasian Journal of Dermatology” This review explores the current understanding of genetic and hormonal influences on male androgenetic alopecia and female pattern hair loss, providing guidance for clinicians but reports no new results.