31 citations
,
October 2005 in “British Journal of Dermatology” This study found that sebum excretion is not increased in women with female pattern hair loss, suggesting nonandrogenic factors may contribute to hair loss in some women without hirsutism.
31 citations
,
January 1989 in “Clinical and Experimental Dermatology” In this study, topical 2% minoxidil did not significantly improve hair density measures in men with male pattern baldness, although there was no deterioration, suggesting a potential prophylactic effect.
28 citations
,
April 2009 in “Annals of laboratory medicine” This study found that the DFS pattern occurs in about 28% of ANA-positive cases and is relatively frequent in autoimmune diseases, contrary to previous observations suggesting no link with these diseases.
26 citations
,
April 2009 in “Australasian Journal of Dermatology” In this study, a 9-year-old girl with female pattern hair loss showed clinical improvement and hair regrowth after six months of daily oral spironolactone.
21 citations
,
August 2013 in “Journal of Dermatological Treatment” This review discusses the mixed evidence and high risk of bias in studies on low-level light therapy for treating androgenetic alopecia and calls for rigorous randomized controlled trials to assess its efficacy.
21 citations
,
January 2007 in “Australasian Journal of Dermatology” This case report describes how a 53-year-old woman with female pattern hair loss experienced further hair regrowth when topical minoxidil was added to her spironolactone treatment after initial results plateaued.
19 citations
,
August 2000 in “International Journal of Dermatology” This article discusses the medical management of male pattern hair loss and reports no new clinical findings.
17 citations
,
July 2003 in “Metabolism-clinical and Experimental” This study found that young women with female-pattern hair loss exhibit increased testosterone production rates while dihydrotestosterone production rates remain within or below the normal range.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article reviews pharmacologic treatments for pattern hair loss and emphasizes integrating them with surgical and nonmedical options, but it does not present new clinical findings.
13 citations
,
October 2011 in “Clinical and Experimental Dermatology” This study found no improvement in male-pattern hair loss after six months of using laser hair-comb therapy in two men.
13 citations
,
October 2002 in “Journal of Biochemical and Biophysical Methods” This study found that men with androgenic alopecia had significantly higher levels of certain urinary steroid metabolites, suggesting increased 5 alpha-reductase activity and possible mild hyperadrenal activity.
12 citations
,
September 2021 in “PLoS ONE” In this study, researchers found that interaction between transcription factor EBF1 and gene WNT10A, influenced by a genetic variant, may play a role in hair shaft formation and anagen shortening in male pattern baldness.
10 citations
,
September 2020 in “Archives of Dermatological Research” Both methods improve hair density and thickness; double-spin may be more effective.
10 citations
,
January 2010 in “PubMed” This article reviews current hair loss treatments, proposing a hypothesis that a combination of drugs, supplements, and therapies may effectively manage hair loss, but presents no new clinical results.
6 citations
,
December 2013 in “Journal of Cutaneous Pathology” This study found that the distribution of mast cell prostaglandin d-synthase in the scalp spatially aligns with the pattern of androgenetic alopecia, suggesting a programmed vulnerability to hair loss.
5 citations
,
January 2020 in “Journal of Dermatology” This study found that temporal hair loss is evident in Korean women with female pattern hair loss, suggesting it should be included in classification systems like the BASP.
5 citations
,
April 2018 in “Journal of Dermatological Science” This study found that the E2-ANGPT2 pathway is involved in hair follicle regulation and that ANGPT2 treatment increased hair density in modeled female pattern hair loss, suggesting potential therapeutic use.
5 citations
,
August 2013 in “Facial plastic surgery clinics of North America” This article discusses managing extensive hair loss with limited transplant options and suggests a frontal forelock-type pattern is effective for both already bald men and younger patients at risk; it reports no new clinical results.
5 citations
,
August 2012 in “Journal of Dermatology” This report presents a case where female pattern hair loss might be linked to tamoxifen use, with increased androgen receptor expression observed in the affected scalp area.
5 citations
,
June 2012 in “Journal of Cosmetic Dermatology” This review discusses female pattern hair loss as distinct from androgenetic alopecia and suggests that clinicians use tools like dermoscopy and histopathology for more accurate diagnosis, without reporting new findings.
4 citations
,
May 2021 in “Journal of The American Academy of Dermatology” This study found no significant genetic correlations between male pattern baldness and COVID-19 outcomes, suggesting that shared genetic factors may not explain the reported association.
4 citations
,
April 2020 in “Journal of Cosmetic Dermatology” This study found that Chinese patients with alopecia areata, female pattern hair loss, and male androgenetic alopecia had significantly lower serum vitamin D levels than healthy individuals.
3 citations
,
December 2016 in “Canadian Urological Association journal” This study suggests that male pattern baldness—especially moderate to severe—is an independent risk factor for prostate cancer and high-grade disease in men undergoing prostate biopsy.
3 citations
,
April 2010 in “Endocrinology” This review discusses the mechanisms of androgenic alopecia and reports no new results; the development of a mouse model for further study is described.
2 citations
,
June 2011 in “Expert Review of Dermatology” This review discusses the characteristics and management options for female pattern hair loss, highlighting the unclear role of androgens and the psychosocial impact, and reports no new clinical results.
1 citations
,
July 2021 in “Current Issues in Molecular Biology” This study found that finasteride treatment of male rats led to changes in their male offspring's testicular gene expression, potentially affecting sperm function in response to odorant-like signals.
August 2024 in “IAHS Medical Journal” This study, conducted among 50 women with female-pattern hair loss, observed that 89% had deficient or insufficient vitamin D levels and also showed low ferritin levels, suggesting these deficiencies may contribute to hair loss.
September 2019 in “Journal of Investigative Dermatology” This study found that co-culturing dermal papilla cells in a 3D structure with adipose-derived stem cells may enhance the expression of hair inductivity markers compared to 2D cultures.
Botulinum toxin injections can reduce hair loss and stimulate new hair growth in some men with male pattern baldness.
September 1997 in “Dermatologic Surgery” This article reviews different grafting strategies for hair restoration surgery in extensive baldness and suggests uniform density grafting offers less detectable results, especially under adverse grooming conditions.