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This study describes the case of a 22-year-old female with alopecia areata linked to vitamin D deficiency, highlighting the importance of early diagnosis and management of deficiency to prevent broader health issues.

In this study, the researchers found that a 28-day topical treatment with a postbiotic ferment complex notably altered the scalp microbiome in women with sensitive scalps, increasing certain bacterial species and decreasing others, while also reportedly alleviating symptoms of sensitive skin syndrome in all participants.

This review discusses the regulation and function of vitamin D and its receptor in skin cells, highlighting their roles in processes such as proliferation inhibition, differentiation, and innate immunity, but reports no new results.

This minireview discusses a proposed model of the vitamin D receptor that explains how 1alpha,25(OH)2D3 can mediate both genomic and rapid responses through different ligand shapes and cellular locations, without presenting new research findings.

This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.

This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.

This review suggests that decreased serum 25-hydroxyvitamin D levels may play a role in different types of non-scarring alopecia, but further studies are needed to explore vitamin D supplementation as a therapeutic option.

In this study, mutations in the vitamin D receptor were identified in Brazilian children with rickets and alopecia, leading to impaired receptor activation and reduced 24-hydroxylase expression.

This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

In this study, the herbal complex of Houttuynia cordata, Perilla frutescens var. acuta, and green tea promoted hair growth in C57BL/6 mice, enhancing regrowth and follicle development compared to controls.

In this study, a Chinese Han family with hereditary vitamin D-resistant rickets was found to have a homozygous missense mutation in the VDR gene, and the affected individual uniquely responded well to treatment with oral calcium and low-dose calcitriol.

This case report observed that after 6 months of treatment with topical cetirizine and oral vitamin D, hair density and quality improved in three girls with congenital hypotrichosis due to ectodermal dysplasia.

This study found that patients with alopecia areata had significantly lower serum 25-Hydroxy vitamin D levels compared to healthy controls, and observed a significant inverse relationship between vitamin D levels and disease severity.

This study observed that women with PCOS have a higher likelihood of vitamin D deficiency, particularly if they are obese, compared to women without PCOS.

This study suggests that the role of vitamin 25(OH)D in the pathogenesis of PCOS and diminished ovarian reserve may be independent of serum vitamin 25(OH)D levels.

This article reviews the potential role of vitamin D supplementation as an adjunct to alemtuzumab therapy in multiple sclerosis management, noting its possible benefits for autoimmune comorbidities and patient adherence, but reports no new clinical results.

This study suggests that unliganded vitamin D receptors in mice may cause more severe skeletal and mineral ion defects than VDR-null conditions, and vitamin D analogues may restore function in specific VDR mutations.

Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.

This study found that multiple vitamins, including B6, increased the number of growing follicles in newborn mouse ovaries in vitro. VB6 promoted primordial follicle activation via the PI3K/Akt signaling pathway in both cultured mouse and human ovarian tissues.

In laboratory settings, this study suggests that Serenoa repens and N-acetyl glucosamine with milk proteins may promote hair follicle vascularization through specific cellular interactions and actions.

This literature review highlights the effectiveness of topical vitamin D (e.g., calcipotriol, calcitriol) in treating vitiligo, emphasizing its role in melanogenesis and as an immunomodulator, either alone or combined with topical corticosteroids, offering minimal side effects.

Vitamin D is crucial for skin health and managing skin diseases.

This review discusses the therapeutic effects of vitamins, highlighting risks such as liver damage from prolonged high doses of vitamin A and hypercalcemia from excessive vitamin D, while noting a case of allergic reaction to vitamin B12.

This study observed that smokers and alcohol consumers with androgenetic alopecia had significantly lower serum levels of antioxidant vitamins, and these habits may trigger earlier onset of alopecia in susceptible individuals.

This study suggests that the vitamin D receptor and hairless gene may directly regulate each other via a transcriptional mechanism, potentially explaining phenotypic similarities between atrichia and VDRRIIa rickets.

This study found that most pathogenic HR mutants associated with atrichia with papular lesions had abolished corepressor activity due to defective interactions with histone deacetylases.

This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.

In this study, the researchers found that vitamin D and calcium signaling in keratinocytes are essential for normal skin regeneration after wounding, with deficiencies significantly delaying wound closure and re-epithelialization in mice.

In this study, male-pattern baldness was strongly associated with a higher risk of keratinocyte cancers, particularly squamous cell carcinoma and melanoma, likely due to increased sun exposure on the scalp rather than androgen levels.