Vitamin B6 Promotes the Activation of Primordial Follicles Through the PI3K/Akt Signaling Pathway

    December 2025 in “ Journal of Ovarian Research ”
    Jianzhong Wen, Wenqian Li, Zhijuan Wang, Luchun Zhang, Yating Huang, Mengjie Weng, Ye Chen, Zhenlin Hou, Hua Zhang, Yuezhou Chen
    TLDR Vitamin B6 may help activate dormant follicles.
    The study demonstrates that Vitamin B6 (VB6) plays a significant role in activating primordial follicles via the PI3K/Akt signaling pathway. This suggests that VB6 could be a potential therapeutic agent for conditions related to follicle activation. The research highlights the importance of the PI3K/Akt pathway in follicular development and the potential of VB6 in influencing this process.
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