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A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

Phospholipase A2 enzymes play key roles in skin health and disease.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Genetic discoveries are leading to new treatments for alopecia areata.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Gene linked to common hair loss found, may lead to new treatments.

Hair loss in African American women, caused by hair care, genetics, and environment, needs more research for better treatment.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

The report suggests that the same underlying issue in blood vessel support may cause angiokeratomas on both the scrotum and eyelids.

Follicle Stimulating Hormone is important for fertility.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

New therapies are being developed that target integrin pathways to treat various diseases.

Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.

Not having enough cystatin M/E protein causes less hair growth and dry skin.

Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.

Various treatments exist for hair loss, but more research is needed for better options.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.