Hair Manifestations of Systemic Disease

The document from 2012 discusses how various hair changes can signal underlying systemic diseases or result from medication use. It notes that a significant number of children with severe malnutrition show hair symptoms, while deficiencies in vitamins and minerals like vitamin C, iron, and zinc can cause distinct hair abnormalities. Heavy metal poisoning is also linked to hair loss. Medications can alter hair color, and chemotherapy is known for causing substantial hair loss, which may return with changes in texture or color. Genetic disorders can lead to unique hair coloration, and certain syndromes present with specific hair shaft abnormalities. Rheumatologic conditions may result in scarring alopecia, and stress can cause hair shedding. Excessive hair growth can be a symptom of systemic disease or medication side effects, and hirsutism in women may indicate endocrine issues. The document emphasizes the importance of investigating sudden hair changes for potential systemic diseases and thoroughly evaluating congenital hair anomalies for associated systemic conditions.