Central Centrifugal Cicatricial Alopecia

July 2018

Kiasha Govender, Ncoza C. Dlova

Central Centrifugal Cicatricial Alopecia CCCA hair loss scarring scalp biopsy topical medications oral medications hair transplantation

TLDR Hair loss in African American women, caused by hair care, genetics, and environment, needs more research for better treatment.

Central Centrifugal Cicatricial Alopecia (CCCA) is a type of hair loss that primarily affects African American women. The exact causes of CCCA are not fully understood, but it is believed to be related to hair care practices, genetics, and environmental factors. Symptoms include hair loss and scarring on the scalp, and diagnosis is typically made through clinical examination and scalp biopsy. Treatment options include topical and oral medications, as well as hair transplantation. However, further research is needed to better understand the causes and treatment of CCCA.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community scarring alopecia awareness in this community

in Chat 33 upvotes 3 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community lost my hair in a single year of treatment at 20 years old

in Finasteride/Dutasteride 86 upvotes 1 year ago

A 20-year-old lost significant hair after one year of treatment, using minoxidil, finasteride, and later dutasteride. They are considering adding RU58841 but are advised to return to finasteride and minoxidil for a year before deciding.

community Wanted to say that Derma rolling and Pumpkin seed oil helped my crown out.

in Treatment 4 upvotes 6 years ago

Derma rolling, pumpkin seed oil, and daily massages helped regrow weak hairs on the crown. Nizoral shampoo and yoga also contributed to reducing scalp pain and stress.

community Finasteride doesn't work for me in 2 years and my bloodtest result just came in.

in Progress Pictures 88 upvotes 2 years ago

A user has been treating hair loss with finasteride for two years without success and is experiencing an itchy scalp with seborrhea. Despite low DHT levels, they are still losing hair, suggesting that DHT might not be the main cause of their hair loss, and they are considering other treatments or causes.

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research What's New in Cicatricial Alopecia?

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New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Factors Affecting the Severity of Central Centrifugal Cicatricial Alopecia