A 40-Year-Old Woman of African Descent with Central Scalp Hair Loss

    January 2022 in “ Clinical Cases in Dermatology
    Nkechi Anne Enechukwu
    TLDR A woman with CCCA has hair loss due to factors like straighteners and tight hairstyles, and treatments include steroids and avoiding certain hair products.
    Central centrifugal cicatricial alopecia (CCCA) is a primary lymphocytic form of scarring hair loss predominantly affecting middle-aged women of African descent. It typically starts at the vertex and spreads centrifugally, often accompanied by itching, pain, and burning sensations. Diagnosis is based on clinical findings and histopathology, with trichoscopy often eliminating the need for a biopsy. Treatment includes potent topical or intralesional corticosteroids, antibiotics, oral corticosteroids, hydroxychloroquine, mycophenolate mofetil, cyclosporine, and minoxidil. Avoiding chemical straighteners and traction hairstyles is recommended.
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