89 citations,
October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
48 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
5 citations,
November 1992 in “Current problems in dermatology” Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
336 citations,
August 2015 in “European Journal of Epidemiology” The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
33 citations,
August 2006 in “Journal der Deutschen Dermatologischen Gesellschaft” Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
11 citations,
March 2007 in “Digestive Diseases and Sciences” The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.
2 citations,
September 2015 in “Clínica e Investigación en Arteriosclerosis” Some skin conditions may increase the risk of heart disease, but are not yet included in cardiovascular prevention guidelines.
October 2022 in “Veterinária notícias/Veterinária Notícias” A 5-year-old Akita with a rare skin condition improved significantly after treatment.
50 citations,
March 2021 in “Journal of investigational allergology & clinical immunology” Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
11 citations,
January 2017 in “Oxidative medicine and cellular longevity” Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
January 2009 in “Springer eBooks” The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.
April 2016 in “Journal of The American Academy of Dermatology” Lichen planus may be associated with a higher risk of metabolic syndrome.
17 citations,
July 1994 in “Journal of Dermatological Science” The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
60 citations,
January 2014 in “Anais Brasileiros De Dermatologia” Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
7 citations,
July 2019 in “Clinics in Dermatology” Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.
44 citations,
August 2010 in “Lupus” Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.
1 citations,
October 2018 in “InTech eBooks” The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
1 citations,
September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
79 citations,
March 2017 in “Dermatologic clinics” Vitiligo affects overall health and self-esteem, needing more research and awareness.
5 citations,
October 2013 in “Veterinary Clinics of North America: Equine Practice” Some horses lose hair without inflammation or itching due to various conditions, and while mainly a cosmetic issue, diagnosis requires examination and biopsies, and breeding is not advised if it's hereditary.
34 citations,
October 2011 in “Pathology Research International” Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.
January 2017 in “Springer eBooks” The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.
137 citations,
January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
426 citations,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
7 citations,
August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
April 2024 in “Molecules/Molecules online/Molecules annual” Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.