Dermatoses of Pregnancy

The 2006 document details the skin conditions that can arise during pregnancy, known as dermatoses of pregnancy, which are influenced by hormonal, immune, metabolic, and vascular changes. It outlines physiologic skin changes like hyperpigmentation and striae, the impact on pre-existing conditions such as psoriasis and lupus erythematosus, and introduces a new classification for pregnancy-specific dermatoses. These include pemphigoid gestationis, a rare autoimmune disorder with potential fetal risk; polymorphic eruption of pregnancy, common in first-time and multiple pregnancies with no fetal risk; intrahepatic cholestasis, which can lead to fetal distress; and atopic eruption of pregnancy, common in those with a history of atopy. The document stresses the importance of accurate diagnosis and treatment, which may involve emollients, topical and systemic corticosteroids, antihistamines, and ursodeoxycholic acid. A retrospective study of 401 patients provided data to assist in differential diagnosis among these conditions.