A Case of Interface Perianal Dermatitis in a Dog: Is This an Unusual Manifestation of Lupus Erythematosus?

September 2006 in “ Veterinary pathology ”

Ingo Gerhauser, A. Strothmann-Lüerssen, Wolfgang Baumgärtner

Discoid Lupus Erythematosus DLE interface dermatitis IgG deposition corticosteroids lupus steroids

TLDR A dog with unusual skin lesions near its tail was successfully treated for a rare form of lupus.

In a 2006 case report, a 4-year-old male Bavarian Mountain Scenthound presented with chronic, erosive lesions in the perianal area, a location not commonly associated with Discoid Lupus Erythematosus (DLE). Despite the absence of the more typical facial involvement, the dog was diagnosed with DLE based on histologic and immunohistologic findings, such as interface dermatitis and linear IgG deposition. Treatment with corticosteroids resulted in complete healing of the lesions. This case highlighted that DLE can manifest in atypical locations like the perianal region and that corticosteroid therapy can be effective in such cases.

View this study on journals.sagepub.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 111 results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 828 upvotes 5 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community This is what Six years of DUT looks like

in Finasteride/Dutasteride 791 upvotes 2 years ago

User had success with dutasteride for hair loss after finasteride didn't work. Some experienced increased cholesterol and debated its relation to DHT.

community is there a pyrilutamide group/discord to discuss results?

in Research/Science 21 upvotes 2 years ago

Discussing results, side effects and potential sources of pyrilutamide for hair loss treatment alongside RU58841 and other treatments such as Minoxidil and finasteride.

community HMI 115 Phase 2 - Leaked pics from Discord

in Research/Science 363 upvotes 8 months ago

The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

community We need to create a Discord KX-826 Monotheray group:

in Research/Science 29 upvotes 2 years ago

The conversation is about starting a Discord group for people using KX-826 as their only treatment for hair loss, excluding those who are not serious or use multiple treatments. Someone agrees with the idea but mentions "GP :3," which is unclear.

community Update: A New Therapeutic Channel - Hair Follicle Glucose Metabolism

in Research/Science 11 upvotes 2 years ago

Hair loss can be treated by correcting glucose metabolism in hair follicles and using equol as a safer DHT blocker. Production of these treatments is starting soon, and a Discord channel is available for more information.

Similar Research

5 / 972 results

research Lupus Erythematosus and the Skin

2 citations, January 2004 in “Elsevier eBooks”

Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.

research Involvement of Scalp and Nails in Lupus Erythematosus

44 citations, August 2010 in “Lupus”

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

research Hair and Nail Involvement in Lupus Erythematosus

18 citations, March 2004 in “Clinics in Dermatology”

Lupus can cause hair loss and nail changes, with treatments available for both.

research Skin

2 citations, January 2011 in “Elsevier eBooks”

Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.

research Primary Cicatricial Alopecias

18 citations, October 2012 in “Dermatologic Clinics”

Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.