August 2023 in “Clinical and experimental dermatology and therapies” This study observed mixed responses to dupilumab in patients with both atopic dermatitis and alopecia areata, suggesting a potential role for Th2 axis dysregulation in alopecia areata.
In this laboratory study, researchers developed and tested two in vitro models to simulate atopic dermatitis using HaCaT cells, finding that azithromycin displayed epithelial-strengthening properties in one model, potentially offering insights for future research on skin disease interventions.
April 2023 in “Journal of Investigative Dermatology” This study reports that improvements to the EczemaNet pipeline, incorporating pixel-level segmentation and data augmentation, enhanced the reliability and interpretability of assessing atopic dermatitis severity from digital images.
April 2023 in “Journal of Investigative Dermatology” This study found that adults with atopic dermatitis who were treated with baricitinib at doses of 2mg or 4mg experienced significant improvements in work productivity, potentially leading to substantial indirect cost savings for employers over 16 weeks.
November 2022 in “Journal of Investigative Dermatology” This study found that innate lymphoid cells-type 1 can induce alopecia areata characteristics in human hair follicles both ex vivo and in vivo, challenging the view of it as solely an autoimmune disease driven by CD8+ T cells.
October 2022 in “Portuguese journal of dermatology and venereology” This case study reports significant improvement in severe atopic dermatitis and alopecia areata symptoms in a patient treated with dupilumab, highlighting the potential for patient selection in optimizing therapeutic outcomes.
January 2022 in “Biocell” This review outlines the potential of mesenchymal stem cells and their derivatives as emerging therapies for atopic dermatitis, but reports no new clinical results; the authors highlight the need for further investigation.
April 2021 in “Journal of Investigative Dermatology” This study found that CD1a-restricted CD4+ T cells responsive to lysyl-phosphatidylglycerol were more frequent in the blood of atopic dermatitis patients, suggesting a potential role in the disease's Th2-mediated pathology.
June 2020 in “Journal of Investigative Dermatology” This study found that spatial transcriptomics can reveal hidden inflammation patterns in atopic dermatitis by correlating epidermal and dermal gene expression levels, improving understanding of skin pathology.
April 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study established a mouse model of atopic dermatitis with overgrowth of Malassezia globosa using olive oil as a vehicle, which caused severe lesions and hair follicle damage.
This study found that neutrophils are crucial for initiating chronic itch in atopic dermatitis and suggest that targeting neutrophils may help alleviate symptoms in this condition.
April 2019 in “International journal of research in dermatology” This case report describes a 6-year-old child with twenty nail dystrophy and alopecia areata of the scalp.
April 2019 in “Journal of Investigative Dermatology” This study suggests that dietary grape powder may reduce the severity of atopic dermatitis in a mouse model, highlighting its potential in both prevention and intervention settings.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers observed a strong association between keloid scars and atopic dermatitis, suggesting a link between keloids and signs of atopy in a diverse patient population.
November 2017 in “British Journal of Dermatology” The electronic version of the Dermatology Life Quality Index is as effective as the paper version, with most patients preferring it.
June 2017 in “Journal of the American Academy of Dermatology” The new cream is safe and effective for mild to moderate atopic dermatitis.
June 2017 in “Journal of The American Academy of Dermatology” Tapinarof cream at 1% concentration is effective and better tolerated for treating atopic dermatitis than the 2% concentration.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
April 2017 in “Journal of Investigative Dermatology” In this study, the novel isoprenylcysteine analog SIG-1451 was shown to inhibit pro-inflammatory cytokine release in various cell-based assays relevant to allergic dermatitis, acting on targets such as IL-4 and IL-6 with potential anti-inflammatory benefits.
February 2016 in “Journal of Allergy and Clinical Immunology” This report highlights a case of disseminated and recurrent infundibulofolliculitis in a 45-year-old African American male and underscores the importance of performing a skin biopsy for diagnosis.
April 2011 in “한국생물공학회 학술대회” This study found that an anti-atopic lotion containing fucoidan helped heal skin damage in hairless mice with atopic dermatitis by reducing skin thickness and modulating immune responses.
February 2009 in “Journal of The American Academy of Dermatology” Atopic dermatitis significantly lowers the quality of life for infants and their families.
April 2021 in “Journal of Investigative Dermatology” This study found that transgender patients on masculinizing hormone therapy had a higher likelihood of developing acne compared to cisgender women, and were more likely to experience AGA compared to cisgender women.
July 2014 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that low levels of calcium and magnesium in blood serum were associated with health issues like hair loss and anxiety among participants from urban and rural Pakistan.
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March 2014 in “Veterinary dermatology” This study reported that the prevalence of atopic dermatitis in cats was higher than previously suggested, with severe nonseasonal pruritus most common, and certain breeds were predisposed.
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March 2025 in “Acta fytotechnica et zootechnica/Acta fytotechnica et zootechnica” This study evaluated quercetin's potential as a treatment for cats with Feline Atopic Skin Syndrome, finding it significantly reduced clinical scores in certain symptom groups like Head-and-Neck Pruritus and Miliary Dermatitis, although improvements in oxidative stress markers were not clearly significant.
This case report describes a pediatric instance of follicular atopic dermatitis in a dark-skinned patient, highlighting its unique clinical and dermoscopic features, such as purplish to brownish scaly papules and specific dermoscopic patterns, which are crucial for enhancing diagnostic accuracy in similar cases.
May 2026 in “International Journal of Advanced Biochemistry Research” In this case study, a three-year-old Labrador with canine atopic dermatitis showed significant improvement in pruritus and skin lesions after treatment with oclacitinib and supportive therapy over a one-month follow-up.
August 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found no clear associations between childhood atopic dermatitis and general cognitive ability, although moderate-to-severe cases may slightly affect specific cognitive components like nonverbal IQ.
March 2022 in “Archives of Veterinary Science” This study found that a homeopathic product reduced skin lesions and oxidative stress related to atopic dermatitis in dogs.