August 2022 in “Turkish journal of veterinary research” This study found that dogs with clinical demodicosis experienced oxidative stress, indicated by higher MDA (a marker of oxidation) and lower antioxidant levels, compared to control and post-treatment groups.
June 2024 in “Current Developments in Nutrition” This study found that a dietary intervention in dogs alleviated atopic dermatitis symptoms by modulating immune responses and skin microbiome composition compared to baseline, but with similar non-significant trends when compared with a positive control diet.
April 2017 in “Journal of Investigative Dermatology” In this study, the novel isoprenylcysteine analog SIG-1451 was shown to inhibit pro-inflammatory cytokine release in various cell-based assays relevant to allergic dermatitis, acting on targets such as IL-4 and IL-6 with potential anti-inflammatory benefits.
December 2019 in “Pubvet” This article discusses the diagnosis and management of allergic dermatoses in dogs, focusing on clinical diagnosis, complementary tests, and various treatment strategies, but it reports no new results.
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January 2023 in “Frontiers in veterinary science” This study found that treatment with a synthesized autophagy inducer improved skin barrier function and hair damage in dogs with atopic dermatitis or hyperadrenocorticism by reducing pro-inflammatory cytokines.