Evaluation of Oxidative Stress on Dogs with Demodicosis

August 2022 in “ Turkish journal of veterinary research ”

Gözde Nur SİVEL, Buğrahan Bekir Yağcı

alopecia erythema pruritus oxidative stress MDA GSH GPx SOD demodicosis hair loss redness itching malondialdehyde glutathione glutathione peroxidase superoxide dismutase

TLDR Demodicosis causes significant oxidative stress in dogs.

The study investigated oxidative stress in 32 dogs, 21 with demodicosis and 11 healthy. Clinical signs in affected dogs included alopecia, erythema, and pruritus. Oxidative stress markers were measured, showing higher MDA (20.30 nmol/ml) and lower antioxidant levels (GSH 4.9 nmol/ml, GPx 0.42 U/l, SOD 4.1 U/l) in dogs with demodicosis compared to post-treatment and control groups. Post-treatment values improved but were still lower than controls. The findings indicate that demodicosis causes significant oxidative stress in dogs.

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