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GlossaryGlutathione Peroxidase (GPx)

enzyme that protects cells by reducing harmful peroxides

Glutathione Peroxidase (GPx) is an enzyme that protects cells from oxidative damage by reducing harmful peroxides, such as hydrogen peroxide, into water and oxygen. It uses glutathione as a substrate to neutralize these peroxides, playing a crucial role in maintaining cellular health and preventing damage that can lead to conditions like alopecia and other oxidative stress-related diseases.

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research Expression of E-SOD, GPX5 mRNAs and Immunoexpression of Cu/ZnSOD in Epididymal Epithelial Cells of Finasteride-Treated Rats

10 citations , September 2008 in “Andrologia”

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

GPX4 mRNA Levels in Polymorphonuclear Neutrophils Are Negatively Correlated with Autoantibody Production, Disease Activity, and Lupus Alopecia in Systemic Lupus Erythematosus

research GPX4 mRNA Levels in Polymorphonuclear Neutrophils Are Negatively Correlated with Autoantibody Production, Disease Activity, and Lupus Alopecia in Systemic Lupus Erythematosus

April 2023 in “Research Square (Research Square)”

Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.

research Hyperandrogenism and Insulin Resistance Modulate Gravid Uterine and Placental Ferroptosis in PCOS-Like Rats

104 citations , June 2020 in “Journal of Endocrinology”

Hyperandrogenism and insulin resistance in PCOS-like rats can lead to pregnancy complications due to increased cell death in the uterus and placenta.

White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases

research White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases

80 citations , April 2011 in “Plant physiology”

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

research Biomarkers of Selenium Status in Dogs

11 citations , January 2016 in “BMC veterinary research”

Urinary Se to creatinine ratio, serum Se, and glutathione peroxidase are effective early biomarkers for selenium status in dogs.

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