January 2026 in “Dermatologic Therapy” This study found that a hair serum containing Acanthus ebracteatus extract improved hair regrowth in men with androgenic alopecia, increasing hair count and density of anagen hairs over a 6-month period, with combination treatments showing early effectiveness.
9 citations
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January 2009 in “International Journal of PharmTech Research” This study found that a herbal oil formulation containing Eclipta alba, Hibiscus rosa sinensis, and Nardostachys jatamansi showed better hair growth effects in wister albino rats compared to 2% minoxidil.
March 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that novel lipid nanoparticle formulations may be suitable for delivering anti-alopecia compounds like minoxidil and finasteride, although their skin penetration was limited.
1 citations
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September 2023 in “Drug development and industrial pharmacy” In this study, researchers developed and optimized squarticles containing rosuvastatin calcium and found that they promoted hair regrowth in rats within 10 days, showing superior results compared to the standard minoxidil treatment.
April 2024 in “AAPS PharmSciTech” New microneedle method improves hair regrowth treatment delivery.
January 2020 in “Brazilian Journal of Health and Pharmacy” This study developed nanostructured lipid carriers for finasteride that demonstrated high encapsulation efficiency and reduced cytotoxicity, suggesting potential as a topical treatment for androgenetic alopecia.
27 citations
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August 2018 in “Therapeutic Delivery” In this study, researchers reviewed recent advances in using nanoencapsulation technology to improve the pharmacological treatment of alopecia, suggesting its potential to enhance drug delivery and reduce adverse effects compared to conventional methods.
October 2024 in “Journal of Advanced Pharmaceutical Technology amp Research” This study found that nanoparticulate trigonelline formulations significantly improved hair length and density in rats with induced alopecia compared to controls and commercial hair oil, though it was not more effective than minoxidil after 30 days.
January 2023 in “Research Square (Research Square)” In this study, CoQ10 and selenium nanoparticles showed potential to alleviate hyperlipidemia and simvastatin-induced side effects in rats, but a triple combination with simvastatin caused intense liver and muscle damage.
October 2023 in “Journal of Indian System of Medicine” This study discusses how Ayurveda approaches the management of premature hair greying differently than contemporary science, emphasizing lifestyle regimens, rejuvenation practices, and the use of herbal drugs rooted in Ayurveda pharmacodynamics.
May 2025 in “Journal of Ayurveda and Integrated Medical Sciences” In this phase 3 clinical trial, participants taking Vedistry Amla + Tablets for hair concerns experienced significant reductions in hair fall and improvements in hair texture, strength, and scalp health over three months, with stable laboratory parameters and increased Vitamin D and antioxidant levels.
In this study, imaging techniques showed that nanostructured lipid carrier formulations distributed ascorbic acid more effectively across skin layers compared to conventional cream formulations, suggesting a better method for skin permeation.
12 citations
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May 2022 in “Plants” This review highlights the potential of nano-phytopharmaceuticals in improving the bioavailability and efficacy of phytochemicals for treating locomotor, dermal, reproductive, and urinary tract disorders, but notes that more clinical and preclinical research is needed to establish their safety and efficacy for human use.
68 citations
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January 2020 in “International Journal of Pharmaceutics” Vitamin C-based nanovesicles effectively treat acne.
October 2024 in “International Journal of Ayurveda Research” This study evaluated the 5α-reductase inhibitory effects of several Ayurvedic herbs and found that Eclipta alba exhibited the highest activity, suggesting its potential for use in treatments for androgenic disorders like alopecia.
4 citations
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May 2022 in “Journal of Drug Delivery Science and Technology” This research observed that nanoliposomes delivering a combination of bioactive peptides significantly promoted hair growth in vitro and in vivo by enhancing the proliferation and function of hair growth-targeted cells in C57BL/6 mice, suggesting a promising approach for treating androgenetic alopecia.
2 citations
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January 2022 in “BioMed Research International” This study found that newly developed nanogels for transdermal delivery of finasteride were stable, showed excellent drug permeation through the skin, and ensured biocompatibility without causing irritation or toxicity.
This study examined the use of Purwaceng extract in shampoo formulations, concluding that a specific formula (Sample F1) showed good stability and safety, suggesting its potential effectiveness for hair health issues like dandruff and hair loss.
19 citations
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July 2024 in “Journal of Cellular and Molecular Medicine” In this study, women with PCOS who took 12 mg of Astaxanthin daily for 8 weeks showed a reduction in certain inflammatory markers and apoptosis-related genes, suggesting potential benefits for managing PCOS, though effects on symptoms like BMI and hirsutism were not significant.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes SH‑1 as a next-generation androgen receptor antagonist designed for localized treatment of androgenetic alopecia, aiming to reverse follicular miniaturization while maintaining endocrine balance. Unlike traditional therapies, SH‑1 offers tissue-specific action, avoiding systemic effects.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a herbal shampoo powder using Ayurvedic herbs and evaluated its properties, finding it effectively cleanses and conditions hair while being free of synthetic additives, suggesting it as a sustainable alternative to conventional liquid shampoos.
18 citations
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August 2019 in “Drug Development and Industrial Pharmacy” This study concludes that phospholipid–polymer hybrid nanoparticles may be an effective delivery system for quercetin in treating androgenic alopecia by improving hair regrowth and preventing hair follicle cell apoptosis in rat models.
1 citations
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December 2023 in “Egyptian Journal of Veterinary Science” In this study, researchers found that a nanoparticle gel derived from Astragalus polysaccharides improved wound healing significantly more than a Gold-Silver nanocomposite gel and untreated controls, with better wound closure observed by the 15th day.
This review highlights various plant-based and herbal treatments that reportedly help prevent hair loss and encourage hair growth. It also explores the molecular mechanisms, identified plant compounds, recent technologies such as nanoarchitectonics, and patents related to hair growth promotion.
June 2026 in “International Journal of Scientific Engineering and Technological Research and Innovations” This review highlights the potential of nanoparticle-based shampoos to improve dandruff treatment and cosmetic performance while noting concerns about nanoparticle toxicity and environmental safety that require further investigation.
June 2026 in “International Journal of Pharmaceutics”
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that a newly developed polyherbal Ayurvedic hair oil significantly enhanced hair growth in albino rats, suggesting its potential as a promising natural formulation for hair regrowth.
December 2024 in “Biological and Pharmaceutical Bulletin” In this study, researchers found that minoxidil nanocrystals delivered using MG-MXD@NP, containing methylcellulose and gum arabic, significantly improved hair growth in mice compared to a standard minoxidil lotion, with enhanced delivery to skin tissues and increased markers of hair follicle stem cell activity.
4 citations
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May 2019 in “Asian Journal of Pharmaceutical Sciences” This study found that a dutasteride tablet formulation using cyclodextrin complex, solubilizing polymer, and surfactant achieved similar bioavailability in beagle dogs to that of a commercial capsule.
November 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that nanostructured lipid carriers loaded with spironolactone might improve localized delivery to hair follicles for treating androgenic alopecia, potentially minimizing systemic side effects.