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Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.

FGF5 gene mutations cause long hair in domestic cats.

Chemical hair straightening can damage hair and health, needing safer alternatives and stricter regulations.

A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.

Peptides, proteins, and growth factors in skincare show promise for improving skin health.

Chitosan-coated nanoparticles can effectively deliver positively charged drugs through the skin using iontophoresis.

Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

A surface with VEGF can specifically capture endothelial cells from flowing fluids.

Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

New therapies are being developed that target integrin pathways to treat various diseases.

New nanocarriers improve drug delivery for disease treatment.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

Significant progress was made in understanding PXE, but effective treatments are still needed.

Deleting MED1 in skin cells causes hair loss and skin changes.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

TGase 3 helps build hair structure by forming strong bonds between proteins.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.