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Finasteride in male rats causes liver and metabolic issues in their offspring.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Testosterone may influence COVID-19 severity and outcomes.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Minoxidil can reduce functions related to androgen receptors.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

CDP is crucial for lung and hair follicle cell development.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Finasteride may cause kidney damage.

Androgens may block hair growth signals, targeting this could treat hair loss.

Excess androgens may cause PCOS, not just be a symptom.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.

Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.