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In this retrospective case series, therapeutic responses to immunomodulatory and incretin-based therapies for Dercum's disease showed considerable individual variation, suggesting these treatments might be exploratory options when surgery isn't feasible, though further controlled studies are needed for definitive conclusions.

This study identified three Ayurvedic compounds that may serve as potential treatments against the macrolide-resistant enzyme murE of *Tropheryma whipplei*, addressing challenges in treating Whipple disease.

In this study, PEG and keratin scaffolds selectively influenced protein release rates based on charge and size, suggesting their potential for targeted delivery of protein therapeutics.

This study found that incorporating steroid hormones into DPPC liposomes altered their physicochemical properties, including size, zeta potential, and phase transition temperatures.

This article reviews the management of excessive pre-ejaculate, highlighting case reports where 5-α-reductase inhibitors, such as finasteride and dutasteride, led to symptom resolution in patients reporting distress due to this condition.

This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.

This study found that adapalene-loaded microemulsions significantly enhanced the drug's penetration through guinea pig skin compared to an aqueous suspension, with factors like surfactant ratios and the water-oil phase balance affecting the transfollicular drug delivery efficiency.

This study found that BBS7 expression is crucial for maintaining Sonic hedgehog signaling activity and periodontal ligament homeostasis, suggesting its downregulation in occlusal hypofunction affects cell migration and angiogenesis.

In this study, researchers analyzed plant materials with high anti-seborrhoeic potential, reviewing current studies on plant extracts that may offer therapeutic effects against seborrhea, suggesting that natural cosmetic formulations could safely reduce seborrhea without causing side effects.

This review explores the complex endocrine functions of human skin and its role as a peripheral endocrine organ, but reports no new clinical results.

This review discusses recent progress in understanding the cellular mechanisms of sebaceous gland development and maintenance, emphasizing the role of stem and progenitor cells in related skin pathologies, and reports no new results.

In this study, Meis1 was found to regulate epidermal homeostasis and act as a proto-oncogenic factor in skin tissues, with differences in expression patterns between normal and tumor cells.

This study found that the steroidal aromatase inhibitor exemestane stimulated proliferation of human osteoblast cells, suggesting both androgen receptor-dependent and independent pathways are involved.

This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.

This study found that inhibiting AP1 transcription factor activity in the suprabasal epidermis of mice alters keratinocyte gene expression, reducing barrier integrity and mimicking human keratoderma.

This study created a comprehensive single-cell atlas of hidradenitis suppurativa tunnels, identifying distinct microenvironmental endotypes linked to specific signaling pathways, suggesting that TNF blockade may not effectively address predominant pathways in many lesions and highlighting the potential for individualized treatment strategies.

In this study, researchers observed that a topical gel containing 20% hypoxia mesenchymal stem cell secretome significantly reduced IL-15 and IFN-γ mRNA expression and baldness by 60% in male Wistar rats with fluconazole-related alopecia.

This study concluded that the receptor-like kinase ERULUS, regulated by auxin, is crucial for modulating cell wall composition and pectin dynamics during root hair growth in Arabidopsis.

This study observed that hepatocyte-like cells in canine circumanal glands are distinct entities that develop from hair follicle sheaths and later appear within sebaceous glands, without forming typical exocrine ducts.

This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.

This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.

This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.

This case report highlights that Sheehan's syndrome can still occur in developed countries due to factors like migration and delayed diagnosis, with diabetes insipidus sometimes masked by adrenal insufficiency.

This review discusses the skin's role in producing hormones and related substances, highlighting their potential in homeostasis and disease management, and reports no new clinical findings.

This study reviews current systemic treatments for hidradenitis suppurativa, highlighting traditional methods and new options like biological agents, and suggests that pharmacological therapies show promise, particularly for non-advanced cases, despite the disease's complex etiology involving factors such as genetics and inflammation.

In this study, electron microscopy of follicular mucinosis showed severe cytoplasmic degeneration in hair follicles, with myelin figures and onion-like lamellar structures, but no indications of mucin release through degeneration or degradation were found.

This study found that Wnt ligands secreted by the hair follicle epithelium are crucial for hair follicle regeneration in adults and could inform treatments for hair disorders like alopecia.

This study found that MDSC exosomes promoted partial hair regrowth and modulated immune responses in mice with alopecia areata, suggesting potential as a treatment for autoimmune diseases.