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RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

Eruptive vellus hair cysts are rare, benign skin lesions that are hard to treat.

Skin lymphoproliferative disorders are hard to diagnose and often linked to systemic diseases, but most have a good prognosis with accurate diagnosis.

Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.

Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Alopecia areata involves specific T-cells, unlike androgenetic alopecia.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Prolactin affects when mice shed and grow hair.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Notch-related genes play a key role in the development and cycling of hair follicles.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.