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This study found that hair follicle cells' growth in vitro is influenced by the concentration of androgens and antiandrogens, with papilla cells and outer root sheath keratinocytes showing distinct sensitivity.

This study found that the in vitro growth of hair follicle cells, particularly papilla cells and outer root sheath keratinocytes, is influenced by different concentrations of androgens and antiandrogens.

This study found that prenatal antiandrogen treatment in female spotted hyenas significantly altered the LH response to GnRH, indicating partial masculinization of their anterior pituitary gland without affecting ovulatory function.

In this study, adolescent male acne patients with normal serum testosterone showed improved outcomes with finasteride plus lifestyle intervention, significantly reducing DHT and free testosterone levels and improving SHBG levels, with minimal adverse effects.

This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.

This review discusses the roles of glucocorticoid and sex hormone receptors in the skin and their clinical importance, but reports no new research findings.

This review discusses the role of antiandrogenic gestagens in treating androgen-dependent skin disorders and highlights the need for dermatologists to collaborate with endocrinologists and gynecologists for effective management.

This article discusses the effectiveness and indications of sex hormone therapy for various skin disorders and emphasizes the importance of avoiding androgen-effective contraceptives, but reports no new clinical results.

This review suggests spearmint tea may lower androgenic hormones in women with hirsutism and related symptoms, though longer treatment and follow-up may be needed for noticeable improvements.

This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.

This study found that combining flutamide with an oral contraceptive significantly reduced hirsutism, acne, and seborrhea in patients after seven months, without significant side effects.

This review discusses treatments for female acne, highlighting the effectiveness of low-dose oral contraceptives and noting their similar side effects to placebo; it reports no new clinical results.

This review discusses the potential usefulness and safety profile of oral antiandrogens for treating frontal fibrosing alopecia, noting possible benefits but acknowledges that finasteride's efficacy remains uncertain.

This review discusses androgen and antiandrogen studies in COVID-19, noting potential impacts on disease severity and suggesting the need for more data on their effectiveness and safety.

This study found that testosterone and dihydrotestosterone significantly decreased the proliferation of papilla cells compared to dermal fibroblasts and outer root sheath keratinocytes in cultured hair follicle cells.

In this study, spearmint tea significantly reduced testosterone levels and improved self-reported hirsutism in women with PCOS, but did not change objective hair growth scores over the short trial period.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.

This study found that fruit extracts from certain Egyptian Sabal species demonstrated significant anti-androgenic activity and potential therapeutic effects against benign prostatic hyperplasia in rat models and cell lines.

This review discusses various sex hormones and related compounds, including estrogens and anabolic steroids, but reports no new findings; it highlights existing literature from 2014 regarding their use and effects.

This study highlights how sex steroids affect hair growth, reporting that testosterone used in masculinizing hormone therapy can lead to androgenetic alopecia in transgender individuals, while feminizing hormone therapy with estradiol and antiandrogens can reduce hirsutism.

This article discusses the complexities of androgen and antiandrogen therapies in women, detailing diagnostic measures, the effects on libido, and the potential benefits of new progestins with antiandrogenic properties, but presents no new empirical findings.

This article states that hormone therapy with estrogens and antiandrogens for transgender females is within an obstetrician-gynecologist's practice scope and involves careful dosing and monitoring to manage short-term thrombotic risks.

This review examines the effects of antiandrogens on female reproductive systems, particularly regarding environmental endocrine disruptors, and presents no new research findings.

This review discusses the role of hormonal influences and antiandrogenic treatments in managing hirsutism and other androgenic manifestations in women, highlighting cyproterone acetate as a beneficial option for cosmetically sensitive patients, and reports no new clinical results.

This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.

This review discusses the use of antiandrogen therapy in dermatology, covering treatments for conditions like acne, hirsutism, and androgenic alopecia but reports no new clinical findings.

This review discusses treatment options for hirsutism in women of childbearing age, focusing on the use of contraceptives, CPA, spironolactone, and third-line therapies, and reports no clinical results.

This systematic review found insufficient evidence to make robust recommendations for using antiandrogen therapies in treating hidradenitis suppurativa/acne inversa and suggests that further randomized controlled trials are necessary.

This article reviews the complex relationship between androgenic hormones and skin disorders, emphasizing the need for further innovative research to understand varying skin responses, but it reports no new findings.