Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data

    Georgios Nikolakis, Athanassios Kyrgidis, Christos C. Zouboulis
    Image of study
    TLDR Antiandrogen therapy for hidradenitis suppurativa lacks strong evidence and needs more research.
    In 2019, a systematic review was conducted to evaluate the effectiveness of antiandrogen therapy for treating hidradenitis suppurativa/acne inversa, a disease that affects the apocrine gland-rich skin areas and is believed to be influenced by hormones, especially androgens. The primary therapeutic options identified were cyproterone acetate, spironolactone, finasteride, and metformin. The review included one randomized controlled crossover trial and seven case series. However, the studies did not provide strong evidence-based recommendations for the use of antiandrogens in the treatment of this disease, suggesting that more randomized controlled trials are needed to determine the role of hormonal treatment as an alternative or concomitant therapy with antibiotics or biologics.
    Discuss this study in the Community →

    Research cited in this study

    25 / 25 results

    Related Community Posts Join

    6 / 747 results

    Similar Research

    5 / 1000+ results