Antiandrogen Therapy of Acne, Hair Loss, and Hirsutism

June 1980 in “ PubMed ”

E Kaiser

antiandrogen therapy hormonal influences hirsutism seborrhea acne hair loss androgenic activity endocrine regulation estrogen gestagen antiandrogenic progestogens cyproterone acetate antiandrogen hormones androgens progesterone

TLDR Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.

The document discussed the hormonal influences on conditions like hirsutism, seborrhea, acne, and hair loss, highlighting the role of androgens produced by the adrenal glands and ovaries. It reviewed the therapeutic use of large doses of estrogen or gestagen since the 1960s, noting varying success. Significant advancements were achieved with the development of antiandrogenic progestogens, particularly cyproterone acetate, which provided satisfactory results for women when applied selectively based on clinical symptoms.

View this study on pubmed.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Related Community Posts Join

6 / 747 results

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 53 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 1 upvotes 2 weeks ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 2 weeks ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Found this meme on a forum……..

in Satire 150 upvotes 11 months ago

The conversation is about a meme related to hair loss that influenced someone to start taking finasteride. Another person agrees that the meme accurately represents the situation.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 2 months ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 160 upvotes 1 year ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

Related Research

4 / 4 results

research Current Aspects of Antiandrogen Therapy in Women

20 citations, January 1999 in “Current Pharmaceutical Design”

Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.

research Antiandrogen And Hormonal Treatment Of Acne

38 citations, October 1996 in “Dermatologic Clinics”

Certain hormone treatments can improve acne and related conditions in women.

research Clinical Applications of Antiandrogens

29 citations, October 1988 in “Journal of Steroid Biochemistry”

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

research Steroid Inhibitors of Androgen-Potentiated Actions on Skin

4 citations, July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

Certain hormones can reduce skin oil and hair growth, potentially helping treat acne and excessive hair in women.