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5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

UV light might cause excessive hair growth by increasing PGE2 in the skin.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Better hair loss models needed for research.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Hidradenitis suppurativa improves with antiandrogen therapy.

Genomic approach finds new possible treatments for hair loss.

The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.

People with common hair loss conditions may have a higher risk of heart disease and related health issues.

DHT affects testicular development and regulates spermatogenesis in some fish.

New drug shows promise for better hair growth in baldness treatment.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.

Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.