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This study found that individuals with androgenetic alopecia had higher scalp microbiome diversity and more complex scalp-gut microbiome networks than those without, suggesting a link between skin-gut microorganisms and hair loss development.

In this 10-patient exploratory study, the researchers found that topical application of 4-aminopyridine 5% combined with microneedling did not improve hair density or quality in men with androgenetic alopecia, suggesting limited efficacy in this context despite promising results in animal wound models.

This study found that GI198745 acts as a time-dependent inhibitor of rat 5α-reductase type 2 but a rapid-equilibrium inhibitor of type 1, potentially making it more effective than finasteride in preventing rat prostate growth.

This study developed a new semiquantitative grading scale for frontal and vertex androgenetic alopecia, which was found to be more sensitive and objective than existing classifications.

This study found that patients with androgenetic alopecia had thinner scalp and subcutaneous tissues, narrower and shorter hair follicles, a lower hair follicle count, and fewer color flow signals compared to healthy volunteers, as measured by 22 MHz ultrasound.

This study found that N-acetyl-cysteine alone or combined with minoxidil improved hair parameters in men with early-onset androgenetic alopecia, with tolerable side effects.

This study highlights how sex steroids affect hair growth, reporting that testosterone used in masculinizing hormone therapy can lead to androgenetic alopecia in transgender individuals, while feminizing hormone therapy with estradiol and antiandrogens can reduce hirsutism.

This study found that the TrichoScan method for evaluating hair loss showed excellent correlation with manual marking and provided more consistent, reproducible results with less variability and operator error.

This article reviews optimal patient selection and donor site quality for successful hair transplant procedures, but reports no new clinical findings.

This study found that a melatonin-loaded microemulsion exhibited controlled release and significant stratum corneum deposition in ex vivo permeation tests, suggesting its potential for further evaluation in treating androgenic alopecia.

This study identified optimal parameters for extracting oil from Urtica dioica roots to maximize phytosterol content, using corn oil and a 1:5 raw material-extract ratio over a 6-hour maceration period.

This study found that women with polycystic ovary syndrome in the Black Sea Region had higher levels of androgens, obesity, and insulin resistance, increasing their risk of metabolic syndrome compared to healthy women.

In this study, a significant positive correlation between clinical hyperandrogenism and free androgen index was found in younger women with PCOS, but not in older women.

This study reports that quantitative trichoscopy, while noninvasive and convenient, provides less accurate hair density data compared to invasive histopathologic examination, which was demonstrated in a sample of adult Chinese individuals without alopecia.

In this study, researchers examined vitamin D levels and blood count parameters in children and adolescents with non-scarring alopecia, finding significant vitamin D deficiency but no significant differences in deficiency or insufficiency across different types of alopecia.

This study reported that both phlebotomy and oral contraceptive pills with cyproterone acetate effectively improved insulin resistance and androgenic profiles in women with PCOS, but OCs had more impact on regularizing menstrual cycles.

This study found that women with female pattern hair loss had significant hormonal imbalances, specifically involving adrenal androgens, suggesting these may play a central role in the condition's development.

This study suggests that pulsed wave photobiomodulation could be a promising treatment for androgenetic alopecia by enhancing dermal papilla cell function through specific light parameters, particularly frequency.

This study found that women with polycystic ovary syndrome showed significant differences in clinical symptoms, hormone levels, and ovarian morphology compared to healthy controls, such as higher body mass index, menstrual irregularities, elevated luteinizing hormone, and polycystic ovarian morphology, suggesting these factors enhance diagnostic accuracy.

This study found that non-alcoholic fatty pancreas disease is significantly more prevalent in women with polycystic ovary syndrome, and is associated with metabolic syndrome, insulin resistance, and hyperandrogenism.

Dutasteride and finasteride can change semen and hormone levels in men.

This study suggests that adding metformin to diet and exercise improves insulin resistance and hyperandrogenism in women with PCOS, though lifestyle changes alone may enhance menstrual cycles.

In this study, an Egyptian cohort with PCOS showed a high prevalence of skin issues like hirsutism and acne compared to controls, with hirsutism linked to higher androgen levels, while other factors also influenced acne and alopecia.

This randomized clinical trial found that oral contraceptives containing desogestrel were associated with more adverse effects on serum lipids and blood pressure compared to those containing drospirenone in patients with polycystic ovary syndrome.

This study suggests that combination drug therapy with spironolactone and either oral contraceptives or dexamethasone effectively manages unresponsive hirsutism, with eight of nine patients achieving satisfactory clinical responses.

This case report describes a 40-year-old man whose secondary infertility, observed after prolonged finasteride use for hair loss, resolved following discontinuation of the drug, resulting in a live birth.

This study found that three months of metformin therapy improved acne, hirsutism, and menstrual irregularities in women with PCOS, along with hormonal and ultrasonographic changes.

Finasteride discontinuation increases sperm count in men.

This study found no significant difference in semen parameters or reproductive hormone levels between men taking low-dose finasteride for androgenic alopecia and those not on the medication.

This study determined that the optimal formulation for caffeine-based hydrogels involves 0.2% caffeine and 2.3% chitosan, based on gel liberation and stability testing.