Cutaneous Manifestations in Patients with Polycystic Ovary Syndrome: Their Prevalence and Correlation with Hormonal and Metabolic Parameters

    October 2025 in “ Zagazig University Medical Journal ”
    S. Zaïd, Nouran E Khedr, Sherif Gaafar, Hend Gaber, Maha Bondok
    TLDR Skin issues like hirsutism, acne, and acanthosis nigricans are common in PCOS and linked to hormone and metabolic changes.
    This study investigated the prevalence of dermatologic manifestations in 53 Egyptian women with PCOS compared to 50 non-PCOS controls. The findings revealed a significantly higher prevalence of hirsutism, androgenic alopecia (AGA), acne, and acanthosis nigricans (AN) in the PCOS group. Specifically, hirsutism was associated with higher levels of total and free testosterone, showing a strong positive correlation. Acne in PCOS patients was more common in younger women, while AN was linked to higher anthropometrics, insulin resistance, and serum prolactin levels. The study concludes that cutaneous manifestations are common in PCOS and can provide clinical insights, with androgen levels influencing hirsutism and metabolic factors contributing to AN.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 30 results

      community I am having Success with RU58841 and 1mm Derma Roller

      in Microneedling  19 upvotes 4 years ago
      A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 1 year ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community Does low HGH leading to hairloss?

      in Research/Science  12 upvotes 2 years ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 1 month ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community Any balding females? I need advice with coping :(

       17 upvotes 9 years ago
      A 27-year-old woman is struggling with hair loss, feeling self-conscious and seeking advice on coping. She mentions trying Minoxidil but is hesitant due to scalp issues and is looking for ways to regain confidence.

    Similar Research

    6 / 1000+ results