Polycystic Ovary Syndrome Patients with High BMI Tend to Have Functional Disorders of Androgen Excess: A Prospective Study

    January 2016 in “ Journal of Nanjing Medical University ”
    Chun Su Yuan, Xiaoqiang Liu, Yundong Mao, Feiyang Diao, Yugui Cui, Jiayin Liu
    Image of study
    TLDR Overweight women with PCOS are more likely to have excess male hormones.
    In a 2016 prospective study involving 125 patients with Polycystic Ovary Syndrome (PCOS) and 130 controls, it was found that PCOS patients with a high Body Mass Index (BMI) were more likely to have functional disorders of androgen excess, indicating hyperandrogenism. The study did not find a significant difference in the prevalence of acne and hirsutism between hyperandrogenic and non-hyperandrogenic subgroups, but those with signs of hyperandrogenism had significantly higher BMI. The study concluded that BMI is a more sensitive diagnostic criterion of clinical/biomedical hyperandrogenism in PCOS than total testosterone, suggesting the importance of weight management in PCOS patients with signs of androgen excess. The study's limitations included the sample size and the sensitivity of the evaluation method.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 21 results

      community How does hair loss and recovery work?

      in Chat  12 upvotes 1 year ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 5 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community C’est terrible - at my wits end

      in Female  450 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community PCOS Hair Loss: What’s Helped Me (and What Didn’t)

      in Treatment  10 upvotes 1 month ago
      OP shares their experience with PCOS-related hair loss, highlighting that addressing vitamin D and ferritin deficiencies, managing hormones with spironolactone, and using gentle hair care products helped improve their condition. They advise against relying on "miracle" hair oils and emphasize the importance of medical evaluation and a combined approach to treatment.

    Similar Research

    5 / 1000+ results