1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
September 2023 in “Biology of reproduction” New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
July 2015 in “Cambridge University Press eBooks” The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.
54 citations,
June 2015 in “Australasian Journal of Dermatology” Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.
37 citations,
January 1997 in “Clinics in Dermatology” Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.
11 citations,
August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
41 citations,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
36 citations,
November 1995 in “Clinical endocrinology” Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
28 citations,
May 1986 in “Clinics in endocrinology and metabolism” New compounds may soon be tested to treat excessive hair growth in women.
11 citations,
January 2001 in “Cambridge University Press eBooks” Androgens can cause hair growth in some areas but hair loss on the scalp.
8 citations,
May 1982 in “Journal of Endocrinology/Journal of endocrinology” Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
60 citations,
September 2001 in “Journal of the American Academy of Dermatology” Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
41 citations,
November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
12 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.
2 citations,
January 2014 in “Turkish Journal of Medical Sciences” TrichoScan effectively diagnoses different types of hair loss and is linked to low iron stores in patients.
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
June 2021 in “International Journal of Ayurvedic Medicine” Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.
42 citations,
July 2021 in “Frontiers in Medicine” Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.
29 citations,
October 2020 in “Environmental health perspectives” Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
April 2021 in “IntechOpen eBooks” Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
1 citations,
February 2017 in “Journal of gynecology and womens health” The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
24 citations,
January 2017 in “Journal of Cutaneous and Aesthetic Surgery” Botulinum toxin was found to be a safe and effective treatment for male pattern baldness in a small test, but more research is needed.
May 2023 in “IntechOpen eBooks” More research is needed to understand how testosterone is maintained in adult males.
May 2009 in “Hair transplant forum international” Androgens affect hair growth and shedding, with genetic and non-genetic factors influencing baldness.
April 2023 in “Medizinische Genetik” Male-pattern hair loss is largely influenced by genetics, with key genes identified.
39 citations,
May 2011 in “European Journal of Clinical Investigation” Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.
82 citations,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
38 citations,
July 2012 in “international journal of endocrinology and metabolism” Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.
Detailed history and physical examination are crucial for diagnosing hair loss.
108 citations,
December 2003 in “Lasers in surgery and medicine” ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.