47 citations,
April 2003 in “Journal of dermatological science” Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.
38 citations,
September 2006 in “Journal of Dermatological Science” Ketoconazole lotion can improve hair regrowth for some people with androgenetic alopecia.
[object Object] 22 citations,
November 2011 in “Journal of Analytical Toxicology” Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
17 citations,
August 2001 in “Australasian journal of dermatology” A woman's liver problems improved after she stopped taking spironolactone.
16 citations,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
15 citations,
January 1998 in “Journal of Clinical Periodontology” Finasteride helps treat hair loss by blocking enzyme activity.
14 citations,
April 2006 in “Expert Review of Dermatology” Antiandrogen therapy helps treat genetic hair loss.
14 citations,
December 1998 in “The Journal of Clinical Endocrinology and Metabolism” MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
9 citations,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
8 citations,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
7 citations,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
5 citations,
November 2004 in “Japanese journal of geriatrics” Male hormones can cause hair loss, but treatments like Minoxidil and Finasteride can help, and targeting TGF-B1 could be a future solution.
5 citations,
March 2001 in “Clinics in Dermatology” Diagnose and manage hair issues in women by checking medical conditions and using personalized treatments.
2 citations,
January 2022 in “Rasayan journal of Chemistry” Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.
2 citations,
November 2017 in “Elsevier eBooks” Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
2 citations,
November 2008 in “Medical Hypotheses” VEGF and its receptor might cause hair loss.
[object Object] 2 citations,
January 2004 in “Enshou saisei” Male pattern baldness is caused by certain cells in hair follicles and could potentially be treated by targeting a specific growth factor, TGF-β1.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
November 2024 in “EMJ Dermatology” A new topical treatment using SAMiRNA technology shows promise in increasing hair growth for androgenetic alopecia.
August 2016 in “Journal of Investigative Dermatology” DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
January 2021 in “International Journal of Dermatology” Possible link between COVID-19 and hair loss; more research needed.
September 2017 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān” Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.
1540 citations,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
99 citations,
August 2003 in “Fertility and Sterility” Too much male hormone is the main cause of Polycystic Ovary Syndrome.
44 citations,
April 2015 in “PubMed” Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
25 citations,
January 2013 in “International Journal of Trichology” Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.
16 citations,
January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
December 2023 in “Biointerface Research in Applied Chemistry” Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.