Search

everythinglearnresearchcommunity

for

Search:↓

High aldosterone and free testosterone levels link to female hair loss; testing aldosterone may predict hypertension risk.

A new method helps detect androgen receptor movement in cells, aiding research on hair loss treatments.

Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.

Continued research and awareness are needed to improve treatments for androgen-dependent diseases.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.

Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Minoxidil can reduce functions related to androgen receptors.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Finasteride reduces AML cell growth by inhibiting androgen receptors.

Hair loss, prostate size, and urinary issues are related due to androgen effects.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.