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Flutamide caused damage to male rat reproductive organs and may affect fertility.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

The mouse models are effective for testing new hair loss treatments.

Future treatments for androgenic alopecia may focus on reactivating hair follicle stem cells and improving drug delivery.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Hair loss, prostate size, and urinary issues are related due to androgen effects.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

New genes and pathways are important for testosterone production and male sexual development.

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

New treatments for male hypogonadism are effective and should be personalized.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.

A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.

Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Bicalutamide may help treat female pattern hair loss.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

MitoQ may help treat hair loss by boosting hair growth pathways.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Baicalin may help treat hair loss by promoting hair follicle growth and activating specific cellular pathways.

Oleanolic acid improved hair growth in mice by affecting hair growth pathways and reducing inflammation.

The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.

A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.