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Finasteride in male rats causes liver and metabolic issues in their offspring.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

Male pattern hair loss negatively affects quality of life, but drug treatments can help.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The boy's hair loss was caused by the tuberculosis drug isoniazid but grew back after stopping the medication.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

Minoxidil and finasteride effectively treat hair loss.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.