TLDR The boy's hair loss was caused by the tuberculosis drug isoniazid but grew back after stopping the medication.
The document describes a case where a 10-year-old boy developed alopecia, specifically from the frontal scalp, during treatment with isoniazid and other anti-tuberculosis drugs. After excluding other causes, isoniazid-induced alopecia was diagnosed. This type of alopecia, known as anagen effluvium, involves a sudden stop in hair growth. The boy's hair began to regrow 3 weeks after stopping isoniazid, with full recovery after 6 weeks, and he was cured of tuberculosis after 6 months without further hair loss. Drug-induced alopecia is rare with anti-tuberculosis medications, and while the mechanism behind isoniazid-induced alopecia is not fully understood, an androgen mechanism is proposed. The case highlights the need to be aware of this potential side effect to maintain patient adherence to tuberculosis therapy.
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44 citations
,
August 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
13 citations
,
January 2011 in “Lung India” Stopping isoniazid can reverse hair loss caused by the drug.
13 citations
,
August 2010 in “Drug safety” Lamotrigine may cause hair loss, affecting treatment compliance and health.
47 citations
,
April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
9 citations
,
February 1996 in “Lancet” Some tuberculosis drugs may cause hair loss, but hair might regrow after treatment or changing the drugs.
147 citations
,
April 1994 in “Drug Safety” Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.
4 citations
,
March 1989 in “The BMJ” Naproxen is not the cause of hair loss in a child; it's due to a toxic event with expected hair regrowth.
4 citations
,
June 2014 in “Journal of Pharmacology and Pharmacotherapeutics” The boy's hair loss was caused by the tuberculosis drug isoniazid but grew back after stopping the medication.
