Isoniazid-Induced Alopecia

In a case report from 2011, a 30-year-old woman undergoing treatment for pulmonary tuberculosis with a regimen including isoniazid experienced hair loss after one month of therapy. Upon discontinuation of isoniazid, while continuing the other drugs, her hair loss decreased and regrowth was observed within two months. This case supports previous findings that isoniazid, along with other antituberculosis drugs such as thiacetazone and ethionamide, can be associated with alopecia. Drug-induced alopecia is generally reversible upon withdrawal of the offending drug. The case emphasizes the importance of physicians being aware of this potential side effect so they can manage patient compliance and provide reassurance if hair loss occurs during treatment.