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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Dutasteride and finasteride affect different cell types differently.

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Two gene areas linked to male pattern baldness found, more research needed.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.