research Adverse Health Effects of Androgen Use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
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research Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome
The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.
research Polycystic Ovary Syndrome: Dermatological Approach
Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.
research Androgens in Women: Role in Androgen-Mediated Cutaneous Disorders
Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
research To Study Hypoactive Sexual Desire Disorder in a Fragile X Carrier Female Successfully Treated with Local Testosterone Application
Local testosterone treatment improved sexual desire in a female with fragile X syndrome.
research Polycystic Ovary Syndrome and NC-CAH: Distinct Characteristics and Common Findings. A Systematic Review
Polycystic Ovary Syndrome (PCOS) is common in women with conditions like anovulation, hirsutism, hair loss, and type 2 diabetes, and it can lead to health risks like heart disease, obesity, insulin resistance, and depression. Non-Classic Congenital Adrenal Hyperplasia (NC-CAH) is also discussed.
research Disorders Linked to Insufficient Androgen Action in Male Children
Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
research The Selective Androgen Receptor Modulator GTx-024 (Enobosarm) Improves Lean Body Mass and Physical Function in Healthy Elderly Men and Postmenopausal Women: Results of a Double-Blind, Placebo-Controlled Phase II Trial
Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
research Androgens and the Menopause
Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
research What Does the Research Say About Androgen Use and Cerebrovascular Events?
Androgen use may increase the risk of stroke, but more research is needed.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
research Androgenetic Alopecia and Insulin Resistance in Young Men
Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.
research A Comment on the Post-Finasteride Syndrome
The true incidence of post-Finasteride syndrome is unclear, and more research is needed.
research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days
Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
research The Post-Finasteride Syndrome: Possible Etiological Mechanisms and Symptoms
Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
research Impact of Hormones on Female Sexual Function and Dysfunction
Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.
research Effects of 5-Alpha Reductase Inhibitors
5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis
The document explains how male reproductive hormones work and affect the body.
research Diagnosis of Hyperandrogenism: Biochemical Criteria
The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
research Genetics and Other Factors in the Etiology of Female Pattern Hair Loss
Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.
research Androgens and Antiandrogens: Impact on Women's Health and Hormone Replacement Therapy
Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
research Penis Endocrinology
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
research The Persistent Effects of 5α-Reductase Inhibitors Used in the Treatment of Androgenic Alopecia on Men’s Health
Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.
research Testosterone Hormone: Clinical Indications, Dysregulation, and Therapeutic Methods
Testosterone is vital for male health, and its deficiency is linked to aging and common health issues.
research An Update on Plant-Derived Anti-Androgens
Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.
research Cardiovascular Safety and Benefits of Testosterone Implant Therapy in Postmenopausal Women: Where Are We?
Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.
research Effects of Lifelong Testosterone Exposure on Health and Disease Using Mendelian Randomization
Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.