research Design, Synthesis and Biological Evaluation of Novel 3-Oxo-4-Oxa-5α-Androst-17β-Amide Derivatives as Dual 5α-Reductase Inhibitors and Androgen Receptor Antagonists
New compounds were made that are promising for prostate cancer therapy.
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90-120 / 847 resultsresearch Analysis of Structural Change in Keratin Fibers Resulting from Chemical Treatments Using Raman Spectroscopy
Chemical hair straightening changes hair proteins and mostly fixes broken bonds.
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
research Synthesis of Minoxidil Conjugates and Their Evaluation as HL-60 Differentiation Agents
Some minoxidil combinations can help differentiate leukemia cells without harming other cells.
research Repair of Damaged Hair Protein Fiber by Jointly Using Transglutaminase and Keratin
Using an enzyme and keratin treatment can significantly repair and strengthen damaged hair.
research Characterization of Human Ovarian Teratoma Hair Using AFM, FT-IR, and Raman Spectroscopy
Teratoma hair is similar to scalp hair but has a rougher surface and lower adhesive force.
research In Vitro Release of Zinc Pyrithione from a Shampoo Base and the Effects of Various Additives on Its Release Rate
Additives like ethanol and propylene glycol increase the release of zinc pyrithione from shampoo.
research Design, Synthesis and Anti-Tumor Evaluation of Novel Thiohydantoin Congeners as Androgen Receptor Antagonists With In Vivo Study
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research Pharmacological Review on Purification of Poisonous Plants According to Ayurveda
Ayurveda can make poisonous plants medicinal through specific purification processes.
research The Melanocyte Photosensory System in Human Skin
Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
research Water Distribution in Human Hair Microstructure Elucidated by Spin Contrast Variation Small-Angle Neutron Scattering
The technique showed that human hair has two main parts, with 68% being rigid and the rest flexible, and water swelling affects its structure.
research Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives
A new method efficiently modifies alkenes to create useful medicinal compounds.
research Enzymes
Enzymes play crucial roles in metabolism, health, and disease management.
research Androgens' Role in Severity and Mortality Rates of COVID-19
Male hormones may increase the severity and death rates of COVID-19.
research Most Frequent Dermatoses in Patients with Kidney Transplantation
Kidney transplant patients often have skin issues, mainly infections.
research Novel Synthesis of Nicotinamide Derivatives with Cytotoxic Properties
Newly made nicotinamide compounds could potentially treat cancer.
research Analysis of Structural Changes in Permanent Waved Human Hair Using Raman Spectroscopy
Permanent waving weakens hair by altering its protein structure.
research Cutaneous Side-Effects of Beta-Adrenergic Blockers
Beta-blockers can cause rare skin side-effects, which usually improve after stopping the medication.
research Potential Medical Uses of Cannabigerol: A Brief Overview
CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.
research Topical Minoxidil Sensitization in Androgenic Alopecia
A small percentage of minoxidil users may develop an allergic skin reaction.
research Acne
Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.
research Chapter 14: Principles of Drug Metabolism
Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
research Smoking and the Skin: Effects and Therapeutic Potential
Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
research The Proximal Promoter of the Human Transglutaminase 3 Gene
The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
research Sulfotransferases, Sulfatases, and Formylglycine-Generating Enzymes: A Sulfation Fascination
The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans
Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.
research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
research Sequence-Structure Based Phylogeny of GPCR Class A Rhodopsin Receptors
The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.
research Tamoxifen for Flutamide/Finasteride-Induced Gynecomastia
Tamoxifen effectively treats gynecomastia without causing impotence.