Demethylation of Methionine and Keratin Damage in Human Hair

    February 2018 in “ Amino acids ”
    Kamila Borowczyk, Joanna Suliburska, Hieronim Jakubowski
    Studysummary This study found that homocysteine-keratin accumulation in human hair increases towards the tips, linked to copper/iron-catalyzed demethylation of methionine, and may contribute to keratin damage.
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    Research cited in this study 2

    1. Method for Chronological Recording of Antigen Appearance in Human Head-Hair Shafts and Its Use for Monitoring Glycation Products in Diabetes Journal of immunological methods · 2006
    2. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999

    Related research 3

    1. Keratin Intermediate Filaments in the Colon: Guardians of Epithelial Homeostasis International journal of biochemistry & cell biology · 2020
    2. Structure and Site of Expression of a Murine Type II Hair Keratin Molecular Biology Reports · 1992
    3. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest It Evolved from Keratinocyte Keratins Journal of Investigative Dermatology · 1989