Search

everythinglearnresearchcommunity

for

Search:↓

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

CDP is crucial for lung and hair follicle cell development.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Neurosteroids show promise for treating epilepsy and more research is needed.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Certain drugs that block specific enzymes can help treat prostate diseases.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.